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Stock Plans and Stock-Based Compensation - Estimated Weighted-Average Grant Date Fair Value (Detail) - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term 6 years 1 month 6 days 6 years 1 month 6 days
Expected volatility 104.00% 105.00%
Risk-free interest rate 0.90% 0.40%
Expected dividend yield 0.00% 0.00%
Weighted-average grant date fair value per share $ 3.91 $ 3.91