<SEC-DOCUMENT>0001193125-14-274625-index.html : 20140721
<SEC-HEADER>0001193125-14-274625.hdr.sgml : 20140721
<ACCEPTANCE-DATETIME>20140721211817
ACCESSION NUMBER:		0001193125-14-274625
CONFORMED SUBMISSION TYPE:	S-1MEF
PUBLIC DOCUMENT COUNT:		4
<REFERENCE-462B>333-195127
FILED AS OF DATE:		20140721
DATE AS OF CHANGE:		20140721
EFFECTIVENESS DATE:		20140721

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CymaBay Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001042074
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				943103561
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1MEF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-197548
		FILM NUMBER:		14985467

	BUSINESS ADDRESS:	
		STREET 1:		7999 GATEWAY BLVD
		STREET 2:		SUITE 130
		CITY:			NEWARK
		STATE:			CA
		ZIP:			94560
		BUSINESS PHONE:		510-293-8800

	MAIL ADDRESS:	
		STREET 1:		7999 GATEWAY BLVD
		STREET 2:		SUITE 130
		CITY:			NEWARK
		STATE:			CA
		ZIP:			94560

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	METABOLEX, INC.
		DATE OF NAME CHANGE:	20090721

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	METABOLEX INC
		DATE OF NAME CHANGE:	19970710
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1MEF
<SEQUENCE>1
<FILENAME>d758487ds1mef.htm
<DESCRIPTION>S-1MEF
<TEXT>
Document 1 - file: d758487ds1mef.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d758487dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d758487dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d758487dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d758487dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g758487logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g758487logo.jpg

</DOCUMENT>
</SEC-DOCUMENT>