<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0002021477-24-000001</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002022157</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>7</amendmentNo>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>07/30/2024</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001041024</issuerCik>
        <issuerName>ROCKWELL MEDICAL, INC.</issuerName>
        <issuerCusip>774374300</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>30142 WIXOM ROAD</com:street1>
          <com:street2>30142 WIXOM ROAD</com:street2>
          <com:city>WIXOM</com:city>
          <com:stateOrCountry>MI</com:stateOrCountry>
          <com:zipCode>48393</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Irrevocable Larson Family Investment Trust</reportingPersonName>
      <citizenshipOrOrganization>TX</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>2750000.00</soleVotingPower>
        <sharedVotingPower>7500.00</sharedVotingPower>
        <soleDispositivePower>2750000.00</soleDispositivePower>
        <sharedDispositivePower>7500.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2757500.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.1</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>ROCKWELL MEDICAL, INC.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>30142 WIXOM ROAD, 30142 WIXOM ROAD, WIXOM, MICHIGAN, 48393.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>The Irrevocable Larson Family Investment Trust</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>3608 Lexington Ave.
Dallas, Texas 75205</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Texas</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>2,757,500</amountBeneficiallyOwned>
        <classPercent>9.096</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>2,750,000</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>7,500</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>2,750,000</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>7,500</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Irrevocable Larson Family Investment Trust</reportingPersonName>
      <signatureDetails>
        <signature>Grayson Linyard</signature>
        <title>Attorney in Fact</title>
        <date>08/02/2024</date>
      </signatureDetails>
    </signatureInformation>
    <signatureComments>Incorporating by reference the Power of Attorney attached to SEC Accession No. 0002021477-24-000005</signatureComments>
  </formData>
</edgarSubmission>
