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Stockholders' Equity - Summary of Common Stock Reserved for Issuance (Details) - shares
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Class of Stock [Line Items]      
Performance based stock options outstanding (in shares) 1,206,905 528,591  
Convertible Preferred Stock (in shares) 1,363,636 0  
Common stock reserved for future issuance (in shares) 19,192,700 2,967,440  
Common stock issuable under pre-funded warrants      
Class of Stock [Line Items]      
Pre-funded warrants outstanding (in shares) 6,300,000 0  
Warrants to purchase common stock      
Class of Stock [Line Items]      
Pre-funded warrants outstanding (in shares) 10,196,268 2,402,442  
Unvested restricted stock awards      
Class of Stock [Line Items]      
Unvested restricted stock (in shares) 891 7,118 13,345
Unvested restricted stock units      
Class of Stock [Line Items]      
Unvested restricted stock (in shares) 125,000 29,289 24,136