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Summary of Significant Accounting Policies - Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Net Earnings per Share    
Securities excluded from diluted loss per share calculation 12,968,474 12,624,103
Options to purchase common stock    
Net Earnings per Share    
Securities excluded from diluted loss per share calculation 8,598,149 8,244,605
Unvested restricted stock awards    
Net Earnings per Share    
Securities excluded from diluted loss per share calculation 146,800 146,800
Unvested restricted stock units    
Net Earnings per Share    
Securities excluded from diluted loss per share calculation 1,452,744 1,461,917
Warrants to purchase common stock    
Net Earnings per Share    
Securities excluded from diluted loss per share calculation 2,770,781 2,770,781