CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY - USD ($)	Public offering COMMON SHARES	Public offering ADDITIONAL PAID-IN CAPITAL	Public offering	At The Market [Member] COMMON SHARES	At The Market [Member] ADDITIONAL PAID-IN CAPITAL	At The Market [Member]	COMMON SHARES	ADDITIONAL PAID-IN CAPITAL	ACCUMULATED DEFICIT	ACCUMULATED OTHER COMPREHENSIVE INCOME	Total
Balance at Dec. 31, 2017							$ 5,177	$ 273,205,730	$ (240,262,376)	$ (35,383)	$ 32,913,148
Balance (in shares) at Dec. 31, 2017							51,768,424
Increase (Decrease) in Shareholders' Equity
Net Loss									(22,749,945)		(22,749,945)
Unrealized Gain on Available-for-Sale Investments										96,327	96,327
Foreign Currency Translation Adjustments										(13,791)	(13,791)
Amount of common stock issued on exercise of stock options								(1,978)			(1,978)
Exercise of Employee Stock Options (in shares)							870
Stock-based Compensation								2,425,919			2,425,919
Balance at Sep. 30, 2018							$ 5,177	275,629,671	(263,012,321)	47,153	12,669,680
Balance (in shares) at Sep. 30, 2018							51,769,294
Balance at Jun. 30, 2018							$ 5,177	275,017,065	(258,042,689)	(90,313)	16,889,240
Balance (in shares) at Jun. 30, 2018							51,768,424
Increase (Decrease) in Shareholders' Equity
Net Loss									(4,969,632)		(4,969,632)
Unrealized Gain on Available-for-Sale Investments										143,868	143,868
Foreign Currency Translation Adjustments										(6,402)	(6,402)
Amount of common stock issued on exercise of stock options								(1,978)			(1,978)
Exercise of Employee Stock Options (in shares)							870
Stock-based Compensation								614,584			614,584
Balance at Sep. 30, 2018							$ 5,177	275,629,671	(263,012,321)	47,153	12,669,680
Balance (in shares) at Sep. 30, 2018							51,769,294
Balance at Dec. 31, 2018							$ 5,703	299,596,257	(272,388,234)	63,148	$ 27,276,874
Balance (in shares) at Dec. 31, 2018							57,034,154				57,034,154
Increase (Decrease) in Shareholders' Equity
Net Loss									(26,825,602)		$ (26,825,602)
Unrealized Gain on Available-for-Sale Investments										10,190	10,190
Foreign Currency Translation Adjustments										(631)	(631)
Amount of common stock issued on exercise of stock options							$ 3	147,897			$ 147,900
Exercise of Employee Stock Options (in shares)							30,000				30,000
Delivery of common stock underlying restricted stock units, net of tax							$ 13	(180,302)			$ (180,289)
Delivery of common stock underlying restricted stock units, net of tax (in shares)							126,973
Issuance of Common Shares	$ 626	$ 17,289,296	$ 17,289,921	$ 44	$ 2,089,164	$ 2,089,208
Issuance of Common Shares (in shares)	6,259,214			437,043
Stock-based Compensation								3,895,041			3,895,041
Balance at Sep. 30, 2019							$ 6,389	322,837,353	(299,213,836)	72,707	$ 23,702,613
Balance (in shares) at Sep. 30, 2019							63,887,384				63,887,384
Balance at Jun. 30, 2019							$ 6,340	320,876,606	(291,358,764)	67,557	$ 29,591,739
Balance (in shares) at Jun. 30, 2019							63,398,704
Increase (Decrease) in Shareholders' Equity
Net Loss									(7,855,072)		(7,855,072)
Unrealized Gain on Available-for-Sale Investments										5,926	5,926
Foreign Currency Translation Adjustments										(776)	(776)
Delivery of common stock underlying restricted stock units, net of tax							$ 6	(84,866)			(84,860)
Delivery of common stock underlying restricted stock units, net of tax (in shares)							62,800
Issuance of Common Shares	$ 43	$ 1,169,199	$ 1,169,242
Issuance of Common Shares (in shares)	425,880
Stock-based Compensation								876,414			876,414
Balance at Sep. 30, 2019							$ 6,389	$ 322,837,353	$ (299,213,836)	$ 72,707	$ 23,702,613
Balance (in shares) at Sep. 30, 2019							63,887,384				63,887,384