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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Cash Flows From Operating Activities:    
Net Loss $ (32,125,858) $ (25,921,284)
Adjustments To Reconcile Net Loss To Net Cash Used In Operating Activities:    
Depreciation and Amortization 650,142 514,362
Stock-based Compensation 4,387,554 7,174,596
Research and Development - Licenses Acquired (Related Party) 1,100,000  
Increase in Inventory Reserves 8,784,000  
Loss on Disposal of Assets 4,752 10,777
Realized Loss on Sale of Investments Available-for-Sale 222,338 792,207
Foreign Currency Translation Adjustment (10,762) 1,306
Changes in Assets and Liabilities:    
Increase in Insurance Receivable (371,217)  
Increase in Accounts Receivable (623,948) (962,338)
Decrease in Inventory (835,641) 343,490
(Increase) Decrease in Other Assets (165,712) 264,975
Increase (Decrease) in Accounts Payable 269,912 (1,636,840)
Increase in Settlement Payable 416,668  
Increase in Other Liabilities 271,889 634,238
Decrease in Deferred License Revenue (2,394,051) (2,328,418)
Changes in Assets and Liabilities (3,432,100) (3,684,893)
Cash Used In Operating Activities (20,419,934) (21,112,929)
Cash Flows From Investing Activities:    
Purchase of Investments Available-for-Sale (20,178,127) (35,733,677)
Sale of Investments Available-for-Sale 33,895,481 51,918,745
Purchase of Equipment (744,256) (1,682,913)
Purchase of Research and Development Licenses (Related Party) (250,000)  
Proceeds on Sale of Assets 400 725
Cash Provided By Investing Activities 12,723,498 14,502,880
Cash Flows From Financing Activities:    
Proceeds from the Issuance of Common Shares 22,000,000 123,603
Common Share Issuance Costs (64,049)  
Proceeds from the Exercise of Employee Stock Options, Net of Tax 67,548  
Repurchase of Common Shares to Pay Employee Withholding Taxes   (2,287,231)
Cash Provided By (Used In) Financing Activities 22,003,499 (2,163,628)
Increase (Decrease) In Cash and Cash Equivalents 14,307,063 (8,773,677)
Cash At Beginning Of Period 8,406,917 17,180,594
Cash At End Of Period 22,713,980 8,406,917
Supplemental Cash Flow Information:    
Change in Unrealized Gain on Marketable Securities Available-for-Sale 109,293 $ 866,031
Research and Development Licenses (Related Party) $ 850,000