CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS’ EQUITY - USD ($)	COMMON SHARES	ACCUMULATED DEFICIT	ACCUMULATED OTHER COMPREHENSIVE INCOME/(LOSS)	Total
Balance at Dec. 31, 2016	$ 268,199,939	$ (214,341,092)	$ (902,548)	$ 52,956,299
Balance (in shares) at Dec. 31, 2016	51,527,711
Increase (Decrease) in Shareholders' Equity
Net Loss		(25,921,284)		(25,921,284)
Unrealized Gain on Available-for-Sale Investments			866,031	866,031
Foreign currency rate changes			1,134	1,134
Issuance of Common Shares	$ 123,603			123,603
Issuance of Common Shares (in shares)	508,384
Shares Issued in Exchange for Services	$ 228,847			228,847
Shares Issued in Exchange for Services (in shares)	50,000
Stock-based compensation	$ 6,945,749			6,945,749
Stock Tendered in Satisfaction of Tax Liabilities	$ (2,287,231)			(2,287,231)
Stock Tendered in Satisfaction of Tax Liabilities (in shares)	(317,671)
Balance at Dec. 31, 2017	$ 273,210,907	(240,262,376)	(35,383)	$ 32,913,148
Balance (in shares) at Dec. 31, 2017	51,768,424			51,768,424
Increase (Decrease) in Shareholders' Equity
Net Loss		(32,125,858)		$ (32,125,858)
Unrealized Gain on Available-for-Sale Investments			109,293	109,293
Foreign currency rate changes			(10,762)	(10,762)
Issuance of Common Shares	$ 21,935,951			21,935,951
Issuance of Common Shares (in shares)	5,541,562
Exercise of Employee Stock Option, Net of Tax	$ 67,548			$ 67,548
Exercise of Employee Stock Option, Net of Tax (in shares)	57,368			267,500
Forfeiture of Restricted Stock (Shares)	(333,200)
Stock-based compensation	$ 4,387,554			$ 4,387,554
Balance at Dec. 31, 2018	$ 299,601,960	$ (272,388,234)	$ 63,148	$ 27,276,874
Balance (in shares) at Dec. 31, 2018	57,034,154			57,034,154