Accrued Liabilities (Details) - USD ($)	Dec. 31, 2018	Dec. 31, 2017
ACCRUED LIABILITIES
Accrued Research & Development Expense	$ 86,820	$ 400,024
Accrued Compensation and Benefits	1,525,599	1,991,874
Other Accrued Liabilities	3,517,342	2,323,814
Total Accrued Liabilities	$ 5,129,761	$ 4,715,712