Inventory (Details) - USD ($)	Dec. 31, 2018	Dec. 31, 2017
Inventory [Line Items]
Raw Materials	$ 3,621,548	$ 10,604,232
Work in Process	256,129	212,505
Finished Goods	1,798,101	2,807,399
Total	5,675,778	13,624,136
Inventory, Noncurrent	1,637,000	5,986,752
inventory reserve	700,000
Inventory reserves and write-offs	8,800,000
Triferic Finished Goods
Inventory [Line Items]
Inventory, Noncurrent	1,600,000	6,000,000
Finished goods inventory	8,000,000	13,500,000
inventory reserve	5,800,000	3,500,000
Inventory reserves and write-offs	8,100,000
Increase in inventory reserves and write-offs		$ 3,500,000
Calcitriol [Member]
Inventory [Line Items]
Inventory reserves and write-offs	$ 700,000