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Summary of Significant Accounting Policies - Revenue Recognition, PPE, Licensing and Research (Details)
1 Months Ended 12 Months Ended 24 Months Ended
Dec. 31, 2016
USD ($)
Oct. 31, 2014
USD ($)
Dec. 31, 2018
USD ($)
agreement
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2018
USD ($)
Revenue Recognition          
Number of distribution and license agreements | agreement     2    
Customers average payment term     30 days    
Distributors average payment term     45 days    
Contract liabilities     $ 14,329,000 $ 16,723,000 $ 14,329,000
Impairment losses     0 0  
Bad-debt expense     0 0  
Contract assets     0 0 0
Revenue performance obligation     $ 14,300,000 16,700,000 14,300,000
Remaining performance obligation practical expedient     true    
Impairment of Long-lived Assets          
Impairments of long-lived assets         0
Research and Product Development          
Product development and research costs     $ 5,642,317 6,321,400  
Investments Available for Sale          
Fair value of investments     $ 10,818,059 24,648,459 10,818,059
Licensing Fees          
Useful life     17 years    
Research and Development          
Research and Development Expense     $ 5,642,317 $ 6,321,400  
Loss Per Share          
Securities excluded from diluted loss per share calculation | shares     9,853,322 7,386,001  
Statutory rate (as a percent)     21.00% 35.00%  
License Agreement Terms [Member]          
Research and Product Development          
Product development and research costs     $ 1,100,000    
Research and Development          
Research and Development Expense     $ 1,100,000    
Baxter Healthcare Organization          
Licensing Fees          
Useful life   10 years      
Minimum          
Property and Equipment          
Useful life     3 years    
Stock-Based Compensation          
Market and performance-based stock unit awards service period     1 year    
Maximum          
Property and Equipment          
Useful life     10 years    
Stock-Based Compensation          
Market and performance-based stock unit awards service period     2 years    
Wanbang Biopharmaceutical          
Revenue Recognition          
Deferred Revenue     $ 3,200,000 $ 3,500,000 3,200,000
Upfront payment $ 4,000,000        
Deferred drug license revenue     $ 300,000 300,000  
Baxter Healthcare Organization          
Revenue Recognition          
Upfront payment benefit percent     25.00%    
Partial Refund     $ 6,600,000    
Upfront payment   $ 20,000,000      
Deferred drug license revenue     2,100,000 2,100,000  
Contract liabilities     11,100,000 $ 13,200,000 11,100,000
Revenue performance obligation     11,100,000   11,100,000
Concentrate Products [Member]          
Revenue Recognition          
Reserve for returns     $ 0   $ 0