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Basis of Presentation, Summary of Significant Accounting Policies and Recent Accounting Pronouncements - Revenue Recognition, PPE, Licensing and Research (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 31, 2014
USD ($)
Sep. 30, 2018
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2018
USD ($)
agreement
shares
Sep. 30, 2017
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shares
Dec. 31, 2017
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Revenue Recognition            
Number of distribution and license agreements | agreement       2    
Customers average payment term       30 days    
Distributors average payment term       45 days    
Impairment losses       $ 0    
Bad-debt expense   $ 0 $ 0 0 $ 0  
Contract assets   0   0    
Revenue performance obligation   15,005,000   $ 15,005,000    
Remaining performance obligation practical expedient       true    
Research and Product Development            
Product development and research costs   808,192 1,304,658 $ 4,033,494 4,195,003  
Investments Available for Sale            
Fair value of investments   13,410,151   13,410,151   $ 24,648,459
Realized gains   2,411 57 6,050 57  
Research and Development            
Research and Development Expense   808,192 1,304,658 4,033,494 4,195,003  
Stock-Based Compensation            
Compensation expense (in dollars)   614,583 1,636,507 $ 2,425,919 $ 6,026,578  
Loss Per Share            
Securities excluded from diluted loss per share calculation | shares       9,341,855 7,806,501  
Baxter Healthcare Organization            
Revenue Recognition            
Upfront payment $ 20,000,000          
Deferred drug license revenue   500,000   $ 1,500,000 $ 1,500,000  
Revenue performance obligation   11,732,000   $ 11,732,000    
Remaining performance obligation practical expedient       true    
Licensing Fees            
Useful life 10 years          
Stock options            
Stock-Based Compensation            
Compensation expense (in dollars)   427,944 1,071,653 $ 967,377 3,275,339  
Restricted stock awards            
Stock-Based Compensation            
Compensation expense (in dollars)   20,222 $ 564,854 1,292,125 $ 2,751,239  
Concentrate Products [Member]            
Revenue Recognition            
Reserve for returns   $ 0   $ 0   $ 0