Consolidated Statements Of Cash Flow - USD ($)	12 Months Ended
Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Cash Flows From Operating Activities:
Net (Loss)	$ (25,921,284)	$ (19,802,916)	$ (14,420,450)
Adjustments To Reconcile Net Loss To Net Cash Used In Operating Activities:
Depreciation and Amortization	514,362	762,368	822,294
Share Based Compensation - Non-employee	228,847
Share Based Compensation- Employees	6,945,749	10,346,284	8,887,977
Restricted Stock Retained in Satisfaction of Tax Liabilities	(2,287,231)		(2,912,859)
Loss on Disposal of Assets	10,777	8,168	5,281
Loss (gain) on Sale of Investments Available for Sale	792,207	26,820	58,095
Changes in Assets and Liabilities:
(Increase) Decrease in Accounts Receivable	(962,338)	(1,162,469)	(574,731)
(Increase) in Inventory	343,490	(6,095,846)	(3,951,595)
(Increase) in Other Assets	264,975	(1,230,084)	(360,303)
Increase (Decrease) in Accounts Payable	(1,636,840)	1,863,018	(1,299,299)
Increase (Decrease) in Other Liabilities	634,238	191,134	(413,652)
Increase (decrease) Deferred License Revenue	(2,099,028)	(2,065,785)	(2,081,668)
Increase (decrease) in Deferred International Partnership Revenue	(229,390)	4,706,670
Changes in Assets and Liabilities	(3,684,893)	(3,793,362)	(8,681,248)
Cash (Used In) Operating Activities	(21,114,235)	(12,452,638)	(13,328,051)
Cash Flows From Investing Activities:
Purchase of Securities Available for Sale	35,733,677	25,781,853	21,800,000
Sale of Investments Available for Sale	51,918,745	24,491,677	1,468,656
Purchase of Equipment	(1,682,913)	(355,264)	(815,002)
Proceeds on Sale of Assets	725	1,000	4,800
Cash Provided by Investing Activities	14,502,880	(1,644,440)	(21,141,546)
Cash Flows From Financing Activities:
Proceeds from the Issuance of Common Shares and Purchase Warrants	123,603	80,161	2,780,187
Cash Provided By (Used In) Financing Activities	(2,163,628)	80,161	(132,672)
Effects of exchange rate changes	1,306	(671)
(Decrease) In Cash	(8,773,677)	(14,017,588)	(34,602,269)
Cash At Beginning Of Period	17,180,594	31,198,182	65,800,451
Cash At End Of Period	$ 8,406,917	17,180,594	$ 31,198,182
Supplemental Cash Flow Information:
Income Taxes Paid		$ 404,527

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