Accrued Liabilities (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
ACCRUED LIABILITIES
Accrued Research & Development Expense	$ 400,024	$ 193,638
Accrued Compensation and Benefits	1,991,874	2,002,767
Other Accrued Liabilities	2,323,814	2,013,746
Total Accrued Liabilities	$ 4,715,712	$ 4,210,151