-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, RlT31Kys6qlK+eVeIVtqZ/HSJDyY0Nz+u2cJOzzRb6ieGzaWhaQVBdkY37yUAJrU eQNsY1fnVMAtex/HKHzkJQ== 0001209191-08-037926.txt : 20080618 0001209191-08-037926.hdr.sgml : 20080618 20080618191610 ACCESSION NUMBER: 0001209191-08-037926 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20080616 FILED AS OF DATE: 20080618 DATE AS OF CHANGE: 20080618 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: STEINMETZ MICHAEL CENTRAL INDEX KEY: 0001166285 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906631 BUSINESS ADDRESS: BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: EVNIN LUKE CENTRAL INDEX KEY: 0001134657 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906632 BUSINESS ADDRESS: STREET 1: ONE CAMBRIDGE CENTER CITY: CAMBRIDGE STATE: MA ZIP: 02142 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH STREET CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: MPM BIO VENTURES I LLC CENTRAL INDEX KEY: 0001263200 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906633 BUSINESS ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOR CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: MPM ASSET MANAGEMENT INVESTORS 1999 LLC CENTRAL INDEX KEY: 0001264820 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906636 BUSINESS ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: BAB BIO VENTURES NV CENTRAL INDEX KEY: 0001263198 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906637 MAIL ADDRESS: STREET 1: 111 HUNTINGTON AVE STREET 2: 31ST FL CITY: BOSTON STATE: MA ZIP: 02199 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: BAB BIO VENTURES LLP CENTRAL INDEX KEY: 0001263197 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906638 BUSINESS ADDRESS: STREET 1: 111 HUNTINGTON AVE STREET 2: 31ST FL CITY: BOSTON STATE: MA ZIP: 02199 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: 111 HUNTINGTON AVE STREET 2: 31ST FL CITY: BOSTON STATE: MA ZIP: 02199 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Pharmasset Inc CENTRAL INDEX KEY: 0001301081 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 000000000 BUSINESS ADDRESS: STREET 1: 303-A COLLEGE ROAD EAST CITY: PRINCETON STATE: NJ ZIP: 08540 BUSINESS PHONE: 609-613-4100 MAIL ADDRESS: STREET 1: 303-A COLLEGE ROAD EAST CITY: PRINCETON STATE: NJ ZIP: 08540 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: MPM BIOVENTURES I LP CENTRAL INDEX KEY: 0001263199 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906634 BUSINESS ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 FORMER NAME: FORMER CONFORMED NAME: MPM BIO VENTURES I LP DATE OF NAME CHANGE: 20030910 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: BB BIOVENTURES L P CENTRAL INDEX KEY: 0001040662 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906639 BUSINESS ADDRESS: STREET 1: 62 DE RUYTURES CITY: CURACAO NETHERLANDS ANTILLES STATE: P8 MAIL ADDRESS: STREET 1: 111 HUNTINGTON AVE 31ST FL CITY: BOSTON STATE: MA ZIP: 02119 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: GADICKE ANSBERT CENTRAL INDEX KEY: 0001134655 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906630 BUSINESS ADDRESS: STREET 1: ONE CAMBRIDGE CENTER CITY: CAMBRIDGE STATE: MA ZIP: 02142 BUSINESS PHONE: 6174259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: MPM BIOVENTURES PARALLEL FUND L P CENTRAL INDEX KEY: 0001067661 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33428 FILM NUMBER: 08906635 BUSINESS ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 61724259200 MAIL ADDRESS: STREET 1: THE JOHN HANCOCK TOWER STREET 2: 200 CLARENDON STREET, 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 FORMER NAME: FORMER CONFORMED NAME: MPM BIO VENTURES PARALLEL FUND L P DATE OF NAME CHANGE: 19980805 4 1 bsf41428_bsf7.xml MAIN DOCUMENT DESCRIPTION X0202 4 2008-06-16 0001301081 Pharmasset Inc VRUS 0001040662 BB BIOVENTURES L P C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001263197 BAB BIO VENTURES LLP C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001263198 BAB BIO VENTURES NV C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001264820 MPM ASSET MANAGEMENT INVESTORS 1999 LLC C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001067661 MPM BIOVENTURES PARALLEL FUND L P C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001263199 MPM BIOVENTURES I LP C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001263200 MPM BIO VENTURES I LLC C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001134657 EVNIN LUKE C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001166285 STEINMETZ MICHAEL C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET, 54TH FLOOR BOSTON MA 02116 0 0 1 0 0001134655 GADICKE ANSBERT C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR BOSTON MA 02116 0 0 1 0 Common Stock 2008-06-16 4 S 0 183587 20.05 D 2473593 I See Footnote Common Stock 2008-06-16 4 S 0 100 20.06 D 2473493 I See Footnote Common Stock 2008-06-16 4 S 0 200 20.08 D 2473293 I See Footnote Common Stock 2008-06-16 4 S 0 3176 20.20 D 2470117 I See Footnote Common Stock 2008-06-16 4 S 0 548 20.22 D 2469569 I See Footnote Common Stock 2008-06-16 4 S 0 160 20.24 D 2469409 I See Footnote Common Stock 2008-06-16 4 S 0 19656 20.25 D 2449753 I See Footnote Common Stock 2008-06-16 4 S 0 2124 20.26 D 2447629 I See Footnote Common Stock 2008-06-16 4 S 0 1850 20.27 D 2445779 I See Footnote Common Stock 2008-06-16 4 S 0 824 20.28 D 2444955 I See Footnote Common Stock 2008-06-16 4 S 0 908 20.29 D 2444047 I See Footnote Common Stock 2008-06-16 4 S 0 33666 20.30 D 2410381 I See Footnote Common Stock 2008-06-16 4 S 0 4341 20.31 D 2406040 I See Footnote Common Stock 2008-06-16 4 S 0 25000 20.32 D 2381040 I See Footnote Common Stock 2008-06-16 4 S 0 600 20.33 D 2380440 I See Footnote Common Stock 2008-06-16 4 S 0 800 20.34 D 2379640 I See Footnote Common Stock 2008-06-16 4 S 0 300 20.35 D 2379340 I See Footnote Common Stock 2008-06-16 4 S 0 400 20.36 D 2378940 I See Footnote Common Stock 2008-06-16 4 S 0 200 20.37 D 2378740 I See Footnote Common Stock 2008-06-16 4 S 0 200 20.38 D 2378540 I See Footnote Common Stock 2008-06-16 4 S 0 500 20.39 D 2378040 I See Footnote Common Stock 2008-06-16 4 S 0 1200 20.40 D 2376840 I See Footnote Common Stock 2008-06-16 4 S 0 100 20.41 D 2376740 I See Footnote Common Stock 2008-06-16 4 S 0 100 20.42 D 2376640 I See Footnote Common Stock 2008-06-16 4 S 0 300 20.43 D 2376340 I See Footnote Common Stock 2008-06-16 4 S 0 200 20.44 D 2376140 I See Footnote Common Stock 2008-06-16 4 S 0 100 20.45 D 2376040 I See Footnote Common Stock 2008-06-16 4 S 0 9 20.46 D 2376031 I See Footnote Common Stock 57353 I See Footnote These shares were sold as follows: 81,689 shares by BB BioVentures, L.P. ("BBBV"), 11,013 shares by MPM BioVentures Parallel Fund, L.P. ("BV PF"), 973 shares by MPM Asset Management Investors 1999 LLC ("AM 1999"), 4,745 shares by MPM BioVentures III, L.P., ("BV III"), 70,558 shares by MPM BioVentures III-QP, L.P. ("BV III QP"), 5,963 shares held by MPM BioVentures III GmbH & Co. Beteiligungs KG ("BV KG"), 2,131 shares by MPM BioVentures III Parallel Fund, L.P. ("BV III PF"), 1,678 shares held by MPM Asset Management Investors 2004 BVIII LLC ("AM BV III"), 4,716 by MPM BioVentures III GP, LP ("BV III GP") and 121 by MPM Capital, L.P. ("MPM LP"). MPM BioVentures I, L.P. ("BV I") and MPM BioVentures I LLC ("BV I LLC") are the direct and indirect general partners of BV PF. BAB BioVentures L.P. ("BAB BV"), BAB BioVentures, N.V. ("BAB NV") and BV I LLC are the direct and indirect general partners of BBBV. Luke Evnin, Michael Steinmetz and Ansbert Gadicke are the managers of AM 1999 and BV I LLC. BV III GP and MPM BioVentures III LLC ("BV III LLC") are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV KG. Luke Evnin, Michael Steinmetz and Ansbert Gadicke are Series A members of BV III LLC and managers of AM BV III. Luke Evnin and Ansbert Gadicke have a controlling interest in MPM LP. Each Reporting Person disclaims beneficial ownership of all such shares except to the extent of their respective proportionate pecuniary interests therein. The shares are held as follows: 1,100,650 by BBBV, 148,378 by BV PF, 13,126 by AM 1999, 63,926 by BV III, 950,686 by BV III QP, 80,340 by BV KG, 28,713 by BV III PF, 22,599 by AM BV III, 63,579 by BV III GP and 1,596 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP. The shares are held as follows: 1,100,606 by BBBV, 148,372 by BV PF, 13,125 by AM 1999, 63,923 by BV III, 950,648 by BV III QP, 80,337 by BV KG, 28,712 by BV III PF, 22,598 by AM BV III, 63,576 by BV III GP and 1,596 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 90 by BBBV, 12 by BV PF, 1 by AM 1999, 5 by BV III, 77 by BV III QP, 6 by BV KG, 2 by BV III PF, 2 by AM BV III and 5 by BV III GP. The shares are held as follows: 1,100,516 by BBBV, 148,360 by BV PF, 13,124 by AM 1999, 63,918 by BV III, 950,571 by BV III QP, 80,331 by BV KG, 28,710 by BV III PF, 22,596 by AM BV III, 63,571 by BV III GP and 1,596 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 1,413 by BBBV, 191 by BV PF, 17 by AM 1999, 81 by BV III, 1,221 by BV III QP, 103 by BV KG, 37 by BV III PF, 29 by AM BV III, 82 by BV III GP and 2 by MPM LP. The shares are held as follows: 1,099,103 by BBBV, 148,169 by BV PF, 13,107 by AM 1999, 63,837 by BV III, 949,350 by BV III QP, 80,228 by BV KG, 28,673 by BV III PF, 22,567 by AM BV III, 63,489 by BV III GP and 1,594 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 244 by BBBV, 33 by BV PF, 3 by AM 1999, 14 by BV III, 211 by BV III QP, 18 by BV KG, 6 by BV III PF, 5 by AM BV III and 14 by BV III GP. The shares are held as follows: 1,098,859 by BBBV, 148,136 by BV PF, 13,104 by AM 1999, 63,823 by BV III, 949,139 by BV III QP, 80,210 by BV KG, 28,667 by BV III PF, 22,562 by AM BV III, 63,475 by BV III GP and 1,594 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 72 by BBBV, 10 by BV PF, 1 by AM 1999, 4 by BV III, 61 by BV III QP, 5 by BV KG, 2 by BV III PF, 1 by AM BV III and 4 by BV III GP. The shares are held as follows: 1,098,787 by BBBV, 148,126 by BV PF, 13,103 by AM 1999, 63,819 by BV III, 949,078 by BV III QP, 80,205 by BV KG, 28,665 by BV III PF, 22,561 by AM BV III, 63,471 by BV III GP and 1,594 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 8,746 by BBBV, 1,179 by BV PF, 104 by AM 1999, 508 by BV III, 7,555 by BV III QP, 638 by BV KG, 228 by BV III PF, 180 by AM BV III, 505 by BV III GP and 13 by MPM LP. The shares are held as follows: 1,090,041 by BBBV, 146,947 by BV PF, 12,999 by AM 1999, 63,311 by BV III, 941,523 by BV III QP, 79,567 by BV KG, 28,437 by BV III PF, 22,381 by AM BV III, 62,966 by BV III GP and 1,581 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 946 by BBBV, 127 by BV PF, 11 by AM 1999, 55 by BV III, 816 by BV III QP, 69 by BV KG, 25 by BV III PF, 19 by AM BV III, 55 by BV III GP and 1 by MPM LP. The shares are held as follows: 1,089,095 by BBBV, 146,820 by BV PF, 12,988 by AM 1999, 63,256 by BV III, 940,707 by BV III QP, 79,498 by BV KG, 28,412 by BV III PF, 22,362 by AM BV III, 62,911 by BV III GP and 1,580 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 823 by BBBV, 111 by BV PF, 10 by AM 1999, 48 by BV III, 711 by BV III QP, 60 by BV KG, 21 by BV III PF, 17 by AM BV III, 48 by BV III GP and 1 by MPM LP. The shares are held as follows: 1,088,272 by BBBV, 146,709 by BV PF, 12,978 by AM 1999, 63,208 by BV III, 939,996 by BV III QP, 79,438 by BV KG, 28,391 by BV III PF, 22,345 by AM BV III, 62,863 by BV III GP and 1,579 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 367 by BBBV, 49 by BV PF, 4 by AM 1999, 21 by BV III, 317 by BV III QP, 27 by BV KG, 10 by BV III PF, 7 by AM BV III, 21 by BV III GP and 1 by MPM LP. The shares are held as follows: 1,087,905 by BBBV, 146,660 by BV PF, 12,974 by AM 1999, 63,187 by BV III, 939,679 by BV III QP, 79,411 by BV KG, 28,381 by BV III PF, 22,338 by AM BV III, 62,842 by BV III GP and 1,578 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 404 by BBBV, 54 by BV PF, 5 by AM 1999, 23 by BV III, 351 by BV III QP, 30 by BV KG, 10 by BV III PF, 8 by AM BV III and 23 by BV III GP. The shares are held as follows: 1,087,501 by BBBV, 146,606 by BV PF, 12,969 by AM 1999, 63,164 by BV III, 939,328 by BV III QP, 79,381 by BV KG, 28,371 by BV III PF, 22,330 by AM BV III, 62,819 by BV III GP and 1,578 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 14,980 by BBBV, 2,019 by BV PF, 179 by AM 1999, 870 by BV III, 12,939 by BV III QP, 1,094 by BV KG, 391 by BV III PF, 307 by AM BV III, 865 by BV III GP and 22 by MPM LP. The shares are held as follows: 1,072,521 by BBBV, 144,587 by BV PF, 12,790 by AM 1999, 62,294 by BV III, 926,389 by BV III QP, 78,287 by BV KG, 27,980 by BV III PF, 22,023 by AM BV III, 61,954 by BV III GP and 1,556 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 1,932 by BBBV, 260 by BV PF, 23 by AM 1999, 112 by BV III, 1,668 by BV III QP, 141 by BV KG, 51 by BV III PF, 39 by AM BV III, 112 by BV III GP and 3 by MPM LP. The shares are held as follows: 1,070,589 by BBBV, 144,327 by BV PF, 12,767 by AM 1999, 62,182 by BV III, 924,721 by BV III QP, 78,146 by BV KG, 27,929 by BV III PF, 21,984 by AM BV III, 61,842 by BV III GP and 1,553 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 11,124 by BBBV, 1,500 by BV PF, 132 by AM 1999, 646 by BV III, 9,608 by BV III QP, 813 by BV KG, 290 by BV III PF, 229 by AM BV III, 642 by BV III GP and 16 by MPM LP. The shares are held as follows: 1,059,465 by BBBV, 142,827 by BV PF, 12,635 by AM 1999, 61,536 by BV III, 915,113 by BV III QP, 77,333 by BV KG, 27,639 by BV III PF, 21,755 by AM BV III, 61,200 by BV III GP and 1,537 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 267 by BBBV, 36 by BV PF, 3 by AM 1999, 16 by BV III, 231 by BV III QP, 20 by BV KG, 7 by BV III PF, 5 by AM BV III and 15 by BV III GP. The shares are held as follows: 1,059,198 by BBBV, 142,791 by BV PF, 12,632 by AM 1999, 61,520 by BV III, 914,882 by BV III QP, 77,313 by BV KG, 27,632 by BV III PF, 21,750 by AM BV III, 61,185 by BV III GP and 1,537 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 356 by BBBV, 48 by BV PF, 4 by AM 1999, 21 by BV III, 307 by BV III QP, 26 by BV KG, 9 by BV III PF, 7 by AM BV III, 21 by BV III GP and 1 by MPM LP. The shares are held as follows: 1,058,842 by BBBV, 142,743 by BV PF, 12,628 by AM 1999, 61,499 by BV III, 914,575 by BV III QP, 77,287 by BV KG, 27,623 by BV III PF, 21,743 by AM BV III, 61,164 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 133 by BBBV, 18 by BV PF, 2 by AM 1999, 8 by BV III, 115 by BV III QP, 10 by BV KG, 3 by BV III PF, 3 by AM BV III and 8 by BV III GP. The shares are held as follows: 1,058,709 by BBBV, 142,725 by BV PF, 12,626 by AM 1999, 61,491 by BV III, 914,460 by BV III QP, 77,277 by BV KG, 27,620 by BV III PF, 21,740 by AM BV III, 61,156 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 178 by BBBV, 24 by BV PF, 2 by AM 1999, 10 by BV III, 154 by BV III QP, 13 by BV KG, 5 by BV III PF, 4 by AM BV III and 10 by BV III GP. The shares are held as follows: 1,058,531 by BBBV, 142,701 by BV PF, 12,624 by AM 1999, 61,481 by BV III, 914,306 by BV III QP, 77,264 by BV KG, 27,615 by BV III PF, 21,736 by AM BV III, 61,146 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 89 by BBBV, 12 by BV PF, 1 by AM 1999, 5 by BV III, 77 by BV III QP, 7 by BV KG, 2 by BV III PF, 2 by AM BV III and 5 by BV III GP. The shares are held as follows: 1,058,442 by BBBV, 142,689 by BV PF, 12,623 by AM 1999, 61,476 by BV III, 914,229 by BV III QP, 77,257 by BV KG, 27,613 by BV III PF, 21,734 by AM BV III, 61,141 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 89 by BBBV, 12 by BV PF, 1 by AM 1999, 5 by BV III, 77 by BV III QP, 6 by BV KG, 3 by BV III PF, 2 by AM BV III and 5 by BV III GP. The shares are held as follows: 1,058,353 by BBBV, 142,677 by BV PF, 12,622 by AM 1999, 61,471 by BV III, 914,152 by BV III QP, 77,251 by BV KG, 27,610 by BV III PF, 21,732 by AM BV III, 61,136 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 222 by BBBV, 30 by BV PF, 3 by AM 1999, 13 by BV III, 192 by BV III QP, 16 by BV KG, 6 by BV III PF, 5 by AM BV III and 13 by BV III GP. The shares are held as follows: 1,058,131 by BBBV, 142,647 by BV PF, 12,619 by AM 1999, 61,458 by BV III, 913,960 by BV III QP, 77,235 by BV KG, 27,604 by BV III PF, 21,727 by AM BV III, 61,123 by BV III GP and 1,536 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 534 by BBBV, 72 by BV PF, 6 by AM 1999, 31 by BV III, 461 by BV III QP, 39 by BV KG, 14 by BV III PF, 11 by AM BV III, 31 by BV III GP and 1 by MPM LP. The shares are held as follows: 1,057,597 by BBBV, 142,575 by BV PF, 12,613 by AM 1999, 61,427 by BV III, 913,499 by BV III QP, 77,196 by BV KG, 27,590 by BV III PF, 21,716 by AM BV III, 61,092 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP. The shares are held as follows: 1,057,553 by BBBV, 142,569 by BV PF, 12,612 by AM 1999, 61,424 by BV III, 913,461 by BV III QP, 77,193 by BV KG, 27,589 by BV III PF, 21,715 by AM BV III, 61,089 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP. The shares are held as follows: 1,057,509 by BBBV, 142,563 by BV PF, 12,611 by AM 1999, 61,421 by BV III, 913,423 by BV III QP, 77,190 by BV KG, 27,588 by BV III PF, 21,714 by AM BV III, 61,086 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 133 by BBBV, 18 by BV PF, 2 by AM 1999, 8 by BV III, 115 by BV III QP, 10 by BV KG, 3 by BV III PF, 3 by AM BV III and 8 by BV III GP. The shares are held as follows: 1,057,376 by BBBV, 142,545 by BV PF, 12,609 by AM 1999, 61,413 by BV III, 913,308 by BV III QP, 77,180 by BV KG, 27,585 by BV III PF, 21,711 by AM BV III, 61,078 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 89 by BBBV, 12 by BV PF, 1 by AM 1999, 5 by BV III, 77 by BV III QP, 6 by BV KG, 3 by BV III PF, 2 by AM BV III and 5 by BV III GP. The shares are held as follows: 1,057,287 by BBBV, 142,533 by BV PF, 12,608 by AM 1999, 61,408 by BV III, 913,231 by BV III QP, 77,174 by BV KG, 27,582 by BV III PF, 21,709 by AM BV III, 61,073 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP. The shares are held as follows: 1,057,243 by BBBV, 142,527 by BV PF, 12,607 by AM 1999, 61,405 by BV III, 913,193 by BV III QP, 77,171 by BV KG, 27,581 by BV III PF, 21,708 by AM BV III, 61,070 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares were sold as follows: 4 by BBBV, 1 by BV PF, 3 by BV III QP and 1 by BV III PF. The shares are held as follows: 1,057,239 by BBBV, 142,526 by BV PF, 12,607 by AM 1999, 61,405 by BV III, 913,190 by BV III QP, 77,171 by BV KG, 27,580 by BV III PF, 21,708 by AM BV III, 61,070 by BV III GP and 1,535 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein. The shares are held by Luke Evnin. By Ansbert Gadicke, managing director of BAB BioVentures NV, the general partner of BAB BioVentures L.P., the general partner of BB BioVentures L.P. /s/ Ansbert Gadicke 2008-06-18 By Ansbert Gadicke, managing director of BAB BioVentures NV, the general partner of BAB BioVentures L.P. /s/ Ansbert Gadicke 2008-06-18 By Ansbert Gadicke, managing director of BAB BioVentures NV /s/ Ansbert Gadicke 2008-06-18 By Luke Evnin, manager of MPM Asset Management Investors 1999 LLC /s/ Luke Evnin 2008-06-18 By Luke Evnin, manager of MPM BioVentures I LLC, the general partner of MPM BioVentures I L.P., the general partner of MPM BioVentures Parallel Fund, L.P. /s/ Luke Evnin 2008-06-18 By Luke Evnin, manager of MPM BioVentures I LLC, the general partner of MPM BioVentures I L.P. /s/ Luke Evnin 2008-06-18 By Luke Evnin, manager of MPM BioVentures I LLC /s/ Luke Evnin 2008-06-18 /s/ Luke Evnin 2008-06-18 /s/ Michael Steinmetz 2008-06-18 /s/ Ansbert Gadicke 2008-06-18 -----END PRIVACY-ENHANCED MESSAGE-----