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Segment and Significant Concentrations - Revenue Information by Segments (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Revenue from External Customer [Line Items]        
Total revenue $ 146,001 $ 132,475 $ 290,781 $ 265,112
System and other revenue        
Revenue from External Customer [Line Items]        
Total revenue 24,838 24,360 49,122 43,074
Reagent and disposable revenue        
Revenue from External Customer [Line Items]        
Total revenue $ 121,163 $ 108,115 $ 241,659 $ 222,038