Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 100,331	$ 112,568
Short-term investments	223,155	210,147
Accounts receivable, less allowance for doubtful accounts of $504 as of June 30, 2016 and $383 as of December 31, 2015	62,828	66,550
Inventory, net	156,815	148,690
Prepaid expenses and other current assets	23,384	18,515
Total current assets	566,513	556,470
Property and equipment, net	151,999	127,639
Investments	55,184	62,175
Other non-current assets	5,665	4,205
Intangible assets, net	22,383	25,241
Goodwill	39,681	39,681
Total assets	841,425	815,411
Current liabilities:
Accounts payable	64,296	57,771
Accrued compensation	35,944	39,015
Accrued royalties	4,730	5,469
Accrued and other liabilities	29,483	27,451
Current portion of deferred revenue	15,116	12,778
Total current liabilities	149,569	142,484
Long-term portion of deferred revenue	7,489	5,538
Convertible senior notes, net	287,005	281,627
Other liabilities	19,665	15,779
Total liabilities	463,728	445,428
Commitments and contingencies (Note 8)
Shareholders’ equity:
Preferred stock, no par value; 5,000,000 shares authorized, none issued or outstanding	0	0
Common stock, no par value; 150,000,000 shares authorized, 72,992,190 and 72,415,317 shares issued and outstanding at June 30, 2016 and December 31, 2015, respectively	454,488	449,704
Additional paid-in capital	282,337	263,429
Accumulated other comprehensive loss, net	(53)	(908)
Accumulated deficit	(359,075)	(342,242)
Total shareholders’ equity	377,697	369,983
Total liabilities and shareholders’ equity	$ 841,425	$ 815,411