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Investments in real estate - Real estate asset sales (Details)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
ft²
Jun. 30, 2022
USD ($)
ft²
Mar. 31, 2022
USD ($)
ft²
Dec. 31, 2022
USD ($)
ft²
property
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jul. 01, 2022
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       74,600,000      
Proceeds from sale of real estate assets and partial interest $ 960,386 $ 548,682   $ 2,200,000      
Proceeds from Noncontrolling Interests       1,542,347 $ 2,026,486 $ 367,613  
Gain on sales of real estate 323,699 $ 214,219   537,918 126,570 154,089  
Contributions from and sales of noncontrolling interests       1,560,129 2,147,061 717,158  
Impairment of real estate       64,969 52,675 48,078  
Noncontrolling Interests              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests       910,506 1,157,668 449,726  
Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests       $ 649,623 $ 989,393 $ 267,432  
100 Binney Street              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²     432,931        
Proceeds from Noncontrolling Interests     $ 713,228        
100 Binney Street | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests     $ 413,615        
300 Third Street              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²   131,963          
Proceeds from Noncontrolling Interests   $ 166,485          
300 Third Street | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests   $ 113,020          
Alexandria Park at 128, 285 Bear Hill Road, 111 and 130 Forbes Blvd, and 20 Walkup Drive              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²   617,043          
Real Estate Property, Ownership Interest Sold   100.00%          
Proceeds from sale of real estate   $ 334,397          
Gain on sales of real estate   202,325          
Other              
Real Estate Properties [Line Items]              
Proceeds from sale of real estate 182,696 47,800          
Gain on sales of real estate 65,109 $ 11,894          
1450 Owens Street              
Real Estate Properties [Line Items]              
Proceeds from Noncontrolling Interests 25,039            
1450 Owens Street | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests $ 10,083            
341 and 343 Oyster Point Boulevard, 7000 Shoreline Court, and 75 and 125 Shoreway Road              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft² 330,379            
Real Estate Property, Ownership Interest Sold 100.00%            
Proceeds from sale of real estate $ 383,635            
Gain on sales of real estate $ 223,127            
3215 Merryfield Row              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft² 170,523            
Proceeds from Noncontrolling Interests $ 149,940            
3215 Merryfield Row | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests $ 42,214            
Summers Ridge Science Park              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft² 316,531            
Proceeds from Noncontrolling Interests $ 159,600            
Summers Ridge Science Park | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests $ 65,097            
7330 and 7360 Carroll Road              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft² 84,442            
Real Estate Property, Ownership Interest Sold 100.00%            
Proceeds from sale of real estate $ 59,476            
Gain on sales of real estate $ 35,463            
Alexandria | 100 Binney Street | Noncontrolling Interests              
Real Estate Properties [Line Items]              
Ownership percentage by noncontrolling owners     70.00%        
Alexandria | 300 Third Street | Noncontrolling Interests              
Real Estate Properties [Line Items]              
Ownership percentage by noncontrolling owners   70.00%          
Alexandria | 1450 Owens Street | Noncontrolling Interests              
Real Estate Properties [Line Items]              
Ownership percentage by noncontrolling owners       75.00%      
Real Estate Property, Ownership Interest Sold             20.00%
Alexandria | 3215 Merryfield Row | Noncontrolling Interests              
Real Estate Properties [Line Items]              
Ownership percentage by noncontrolling owners 70.00%            
Alexandria | Summers Ridge Science Park | Noncontrolling Interests              
Real Estate Properties [Line Items]              
Ownership percentage by noncontrolling owners 70.00%            
Future development | 1450 Owens Street              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft² 191,000            
North America              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       41,800,000      
Proceeds from sale of real estate assets and partial interest       $ 2,222,296      
Proceeds from sale of real estate       1,000,000      
Proceeds from Noncontrolling Interests       1,200,000      
Impairment of real estate       44,100      
North America | Additional Paid-In Capital              
Real Estate Properties [Line Items]              
Contributions from and sales of noncontrolling interests $ 117,394 $ 113,020   $ 644,029      
North America | Future development              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       6,665,029      
San Francisco Bay Area              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       600,000      
Impairment of real estate   $ 38,300          
San Francisco Bay Area | Future development              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       610,000      
Other markets              
Real Estate Properties [Line Items]              
Impairment of real estate       $ 20,900      
Number of properties impaired | property       10      
Other markets | Future development              
Real Estate Properties [Line Items]              
Area of Real Estate Property | ft²       1,644,994