Accrued Expenses - Accrued Expenses (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Payables And Accruals [Abstract]
Research and development expenses	$ 3,374	$ 1,849
Payroll other employee-related expenses	528	1,615
Professional services	380	489
Other	245	141
Interest on debt	104	102
Total	$ 4,631	$ 4,196