X0306 4 2018-04-03 0 0001035354 Eloxx Pharmaceuticals, Inc. ELOX 0001726027 Shabtai Gilad C/O ELOXX PHARMACEUTICALS, INC. 950 WINTER STREET, 4TH FLOOR NORTH WALTHAM MA 02451 0 0 1 0 Common Stock 2018-04-03 4 P 0 5700 9.41 A 3274170 D Common Stock 2018-04-04 4 P 0 2600 9.58 A 3276770 D The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.39 to $9.413, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnotes (1) and (2) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.50 to $9.69666, inclusive. /s/ Gregory Weaver, Attorney-in-Fact 2018-04-05