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Stock-based Compensation - Transactions Related to Stock Options Awarded to Employees and Directors (Detail) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Amount    
Options outstanding at December 31, 2022 249,403  
Granted 195,895  
Forfeited (15,638)  
Options outstanding at March 31, 2023 429,660 249,403
Options exercisable at March 31, 2023 109,601  
Weighted average exercise price    
Options outstanding at December 31, 2022 $ 105.87  
Granted 4.27  
Forfeited 22.41  
Options outstanding at March 31, 2023 62.59 $ 105.87
Options exercisable at March 31, 2023 $ 171.38  
Weighted average remaining contractual life    
Options outstanding 6 years 9 months 7 days 8 years 1 month 13 days
Options exercisable 7 years 3 months 3 days  
Aggregate intrinsic value    
Options outstanding $ 10 $ 3
Options exercisable $ 10