Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

Valero Energy Corporation Benefit Plans Administrative Committee:

We consent to the incorporation by reference in the Registration Statement (File No. 333-136333) on Form S-8 of Valero Energy Corporation of our report dated June 28, 2010, with respect to the statements of net assets available for benefits of the Premcor Retirement Savings Plan as of December 31, 2009 and 2008, and the related statements of changes in net assets available for benefits for the years then ended, and the supplemental schedule H, line 4i — schedule of assets (held at end of year) as of December 31, 2009, which report appears in the December 31, 2009 Annual Report on Form 11-K of the Premcor Retirement Savings Plan.

/s/ KPMG LLP  

San Antonio, Texas
June 28, 2010