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Note 5 - Intangible Assets, Net - Intangible Assets (Details) - USD ($)
6 Months Ended
Jun. 30, 2018
Dec. 31, 2017
Cost $ 2,691,935 $ 1,644,308
Accumulated Amortization 1,780,843 1,546,383
Net Book Value 911,092 97,925
eClinical Customer List [Member]    
Cost 1,392,701 1,392,701
Accumulated Amortization 1,392,701 1,392,701
Net Book Value $ 0 0
Finite-Lived Intangible Asset, Useful Life 3 years  
Promasys B.V. Customer List [Member]    
Cost $ 115,607 118,780
Accumulated Amortization 115,607 32,994
Net Book Value $ 0 85,786
Finite-Lived Intangible Asset, Useful Life 15 years  
Promasys B.V. Software Code [Member]    
Cost $ 72,837 72,837
Accumulated Amortization 67,981 60,698
Net Book Value $ 4,856 12,139
Finite-Lived Intangible Asset, Useful Life 5 years  
Promasys B.V. URLs/Website [Member]    
Cost $ 58,387 59,990
Accumulated Amortization 58,387 59,990
Net Book Value $ 0 0
Finite-Lived Intangible Asset, Useful Life 3 years  
Acuity Software Code [Member]    
Cost $ 1,052,403 0
Accumulated Amortization 146,167 0
Net Book Value $ 906,236 $ 0
Finite-Lived Intangible Asset, Useful Life 3 years