X0306 4 2020-11-11 0 0001358762 REATA PHARMACEUTICALS INC RETA 0001034320 WORTLEY MICHAEL D 5320 LEGACY DRIVE PLANO TX 75024 0 1 0 0 Chief Legal Officer Class A common stock 2020-11-11 4 C 0 51429 A 51429 D Class A common stock 2020-11-11 4 S 0 2112 175.9434 D 49317 D Class A common stock 2020-11-11 4 S 0 2190 177.2405 D 47127 D Class A common stock 2020-11-11 4 S 0 9386 178.0968 D 37741 D Class A common stock 2020-11-11 4 S 0 16608 179.0476 D 21133 D Class A common stock 2020-11-11 4 S 0 10552 180.2422 D 10581 D Class A common stock 2020-11-11 4 S 0 7971 180.9257 D 2610 D Class A common stock 2020-11-11 4 S 0 2100 182.0586 D 510 D Class A common stock 2020-11-11 4 S 0 410 182.6421 D 100 D Class A common stock 2020-11-11 4 S 0 100 184.00 D 0 D Employee Stock Option (right to buy) 11.00 2020-11-11 4 M 0 12245 0.00 D 2026-05-25 Class B common stock 12245 0 D Employee Stock Option (right to buy) 17.43 2020-11-11 4 M 0 39184 0.00 D 2025-03-31 Class B common stock 39184 0 D Class B common stock 2020-11-11 4 M 0 12245 11.00 A Class A common stock 12245 12245 D Class B common stock 2020-11-11 4 M 0 39184 17.43 A Class A common stock 39184 51429 D Class B common stock 2020-11-11 4 C 0 51429 D Class A common stock 51429 0 D The Class B common stock is convertible into Class A common stock on a one-for-one basis at the holder's election at any time. The conversion right of the Class B common stock has no expiration date. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $175.61 to $175.585. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $176.68 to $177.60. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $177.61 to $178.60. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $178.62 to $179.47. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $179.61 to $180.565. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $180.63 to $181.57. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $181.62 to $182.60. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions on one day at prices ranging from $182.61 to $182.66. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The options, representing a right to purchase a total of 39,185 shares, vested in sixteen equal quarterly installments beginning on August 25, 2016. The options, representing a right to purchase a total of 39,184 shares, vested as to 14,204 shares on April 1, 2016 and the remainder vested in twelve equal quarterly installments thereafter. /s/ Tracy Herson, attorney-in-fact 2020-11-12