X0202 4 2007-07-16 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001033409 ESHELMAN FREDRIC N 6814 TOWLES ROAD WILMINGTON NC 28409 1 1 0 0 CEO Common Stock 2007-07-16 4 S 0 100 38.69 D 8396026 D Common Stock 2007-07-16 4 S 0 1000 38.70 D 8395026 D Common Stock 2007-07-16 4 S 0 1400 38.71 D 8393626 D Common Stock 2007-07-16 4 S 0 700 38.72 D 8392926 D Common Stock 2007-07-16 4 S 0 1000 38.73 D 8391926 D Common Stock 2007-07-16 4 S 0 1496 38.74 D 8390430 D Common Stock 2007-07-16 4 S 0 1104 38.75 D 8389326 D Common Stock 2007-07-16 4 S 0 2300 38.76 D 8387026 D Common Stock 2007-07-16 4 S 0 500 38.77 D 8386526 D Common Stock 2007-07-16 4 S 0 200 38.78 D 8386326 D Common Stock 2007-07-16 4 S 0 400 38.79 D 8385926 D Common Stock 2007-07-16 4 S 0 700 38.80 D 8385226 D Common Stock 2007-07-16 4 S 0 900 38.81 D 8384326 D Common Stock 2007-07-16 4 S 0 2422 38.82 D 8381904 D Common Stock 2007-07-16 4 S 0 6773 38.83 D 8375131 D Common Stock 2007-07-16 4 S 0 3901 38.84 D 8371230 D Common Stock 2007-07-16 4 S 0 2800 38.85 D 8368430 D Common Stock 2007-07-16 4 S 0 1111 38.86 D 8367319 D Common Stock 2007-07-16 4 S 0 993 38.87 D 8366326 D Common Stock 2007-07-16 4 S 0 943 38.88 D 8365383 D Common Stock 2007-07-16 4 S 0 3457 38.89 D 8361926 D Common Stock 2007-07-16 4 S 0 1391 38.90 D 8360535 D Common Stock 2007-07-16 4 S 0 409 38.91 D 8360126 D Common Stock 2007-07-16 4 S 0 400 38.92 D 8359726 D Common Stock 2007-07-16 4 S 0 700 38.93 D 8359026 D Common Stock 2007-07-16 4 S 0 300 38.94 D 8358726 D Common Stock 2007-07-16 4 S 0 900 38.95 D 8357826 D Common Stock 2007-07-16 4 S 0 1100 38.96 D 8356726 D Common Stock 2007-07-16 4 S 0 300 38.97 D 8356426 D Common Stock 2007-07-16 4 S 0 1796 38.98 D 8354630 D This Form 4 is 3 of 4 Forms 4 being filed to report the sale of stock on July 16, 2007 pursuant to the 10b5-1 trading plan adopted by the Reporting Person. Lisa C. Noecker attorney-in-fact for Fred N. Eshelman 2007-07-17