X0202 4 2007-07-16 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001033409 ESHELMAN FREDRIC N 6814 TOWLES ROAD WILMINGTON NC 28409 1 1 0 0 CEO Common Stock 2007-07-16 4 S 0 500 38.37 D 8417026 D Common Stock 2007-07-16 4 S 0 400 38.38 D 8416626 D Common Stock 2007-07-16 4 S 0 800 38.39 D 8415826 D Common Stock 2007-07-16 4 S 0 400 38.40 D 8415426 D Common Stock 2007-07-16 4 S 0 500 38.41 D 8414926 D Common Stock 2007-07-16 4 S 0 200 38.42 D 8414726 D Common Stock 2007-07-16 4 S 0 300 38.43 D 8414426 D Common Stock 2007-07-16 4 S 0 300 38.44 D 8414126 D Common Stock 2007-07-16 4 S 0 539 38.45 D 8413587 D Common Stock 2007-07-16 4 S 0 1161 38.46 D 8412426 D Common Stock 2007-07-16 4 S 0 1000 38.47 D 8411426 D Common Stock 2007-07-16 4 S 0 1500 38.48 D 8409926 D Common Stock 2007-07-16 4 S 0 1000 38.49 D 8408926 D Common Stock 2007-07-16 4 S 0 400 38.50 D 8408526 D Common Stock 2007-07-16 4 S 0 300 38.51 D 8408226 D Common Stock 2007-07-16 4 S 0 1300 38.52 D 8406926 D Common Stock 2007-07-16 4 S 0 370 38.53 D 8406556 D Common Stock 2007-07-16 4 S 0 900 38.54 D 8405656 D Common Stock 2007-07-16 4 S 0 530 38.55 D 8405126 D Common Stock 2007-07-16 4 S 0 1300 38.56 D 8403826 D Common Stock 2007-07-16 4 S 0 800 38.57 D 8403026 D Common Stock 2007-07-16 4 S 0 100 38.58 D 8402926 D Common Stock 2007-07-16 4 S 0 700 38.60 D 8402226 D Common Stock 2007-07-16 4 S 0 300 38.61 D 8401926 D Common Stock 2007-07-16 4 S 0 100 38.62 D 8401826 D Common Stock 2007-07-16 4 S 0 300 38.64 D 8401526 D Common Stock 2007-07-16 4 S 0 2700 38.65 D 8398826 D Common Stock 2007-07-16 4 S 0 1100 38.66 D 8397726 D Common Stock 2007-07-16 4 S 0 1100 38.67 D 8396626 D Common Stock 2007-07-16 4 S 0 500 38.68 D 8396126 D This Form 4 is 2 of 4 Forms 4 being filed to report the sale of stock on July 16, 2007 pursuant to the 10b5-1 trading plan adopted by the Reporting Person. Lisa C. Noecker attorney-in-fact for Fred N. Eshelman 2007-07-17