X0202 4 2007-06-01 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001033409 ESHELMAN FREDRIC N 6814 TOWLES ROAD WILMINGTON NC 28409 1 1 0 0 CEO Common Stock 2007-06-01 4 S 0 541 36.91 D 8621627 D Common Stock 2007-06-01 4 S 0 1530 36.92 D 8620097 D Common Stock 2007-06-01 4 S 0 2870 36.93 D 8617227 D Common Stock 2007-06-01 4 S 0 1700 36.94 D 8615527 D Common Stock 2007-06-01 4 S 0 1100 36.95 D 8614427 D Common Stock 2007-06-01 4 S 0 1372 36.96 D 8613055 D Common Stock 2007-06-01 4 S 0 1228 36.97 D 8611827 D Common Stock 2007-06-01 4 S 0 1900 36.98 D 8609927 D Common Stock 2007-06-01 4 S 0 500 36.99 D 8609427 D Common Stock 2007-06-01 4 S 0 2900 37.00 D 8606527 D Common Stock 2007-06-01 4 S 0 600 37.01 D 8605927 D Common Stock 2007-06-01 4 S 0 600 37.02 D 8605327 D Common Stock 2007-06-01 4 S 0 1513 37.03 D 8603814 D Common Stock 2007-06-01 4 S 0 200 37.04 D 8603614 D Common Stock 2007-06-01 4 S 0 569 37.05 D 8603045 D Common Stock 2007-06-01 4 S 0 218 37.06 D 8602827 D Common Stock 2007-06-01 4 S 0 200 37.07 D 8602627 D Common Stock 2007-06-01 4 S 0 200 37.08 D 8602427 D Common Stock 2007-06-01 4 S 0 300 37.09 D 8602127 D Common Stock 2007-06-01 4 S 0 100 37.10 D 8602027 D Common Stock 2007-06-01 4 S 0 125 37.12 D 8601902 D Common Stock 2007-06-01 4 S 0 75 37.13 D 8601902 D Common Stock 2007-06-01 4 S 0 100 37.17 D 8601727 D Common Stock 2007-06-01 4 S 0 100 37.18 D 8601627 D Common Stock 2007-06-01 4 S 0 100 37.19 D 8601527 D Common Stock 2007-06-01 4 S 0 200 37.21 D 8601327 D Common Stock 2007-06-01 4 S 0 84 37.22 D 8601243 D Common Stock 2007-06-01 4 S 0 16 37.23 D 8601227 D Common Stock 2007-06-01 4 S 0 300 37.24 D 8600927 D Common Stock 2007-06-01 4 S 0 100 37.26 D 8600827 D This Form 4 is 2 of 3 Forms 4 being filed to report the sale of stock on June 1, 2007 pursuant to the 10b5-1 trading plan adopted by the Reporting Person. Lisa C. Noecker attorney-in-fact for Fred N. Eshelman 2007-06-05