X0202 4 2007-02-26 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001033409 ESHELMAN FREDRIC N 6814 TOWLES ROAD WILMINGTON NC 28409 1 1 0 0 CEO Common Stock 2007-02-26 4 S 0 500 32.95 D 9223260 D Common Stock 2007-02-26 4 S 0 100 32.96 D 9223160 D Common Stock 2007-02-26 4 S 0 400 33.00 D 9222760 D Common Stock 2007-02-26 4 S 0 200 33.01 D 9222560 D Common Stock 2007-02-26 4 S 0 900 33.02 D 9221660 D Common Stock 2007-02-26 4 S 0 800 33.03 D 9220860 D Common Stock 2007-02-26 4 S 0 1200 33.04 D 9219660 D Common Stock 2007-02-26 4 S 0 100 33.05 D 9219560 D Common Stock 2007-02-26 4 S 0 800 33.06 D 9218760 D Common Stock 2007-02-26 4 S 0 1600 33.07 D 9217160 D Common Stock 2007-02-26 4 S 0 2000 33.08 D 9215160 D Common Stock 2007-02-26 4 S 0 2381 33.09 D 9212779 D Common Stock 2007-02-26 4 S 0 2647 33.10 D 9210132 D Common Stock 2007-02-26 4 S 0 2272 33.11 D 9207860 D Common Stock 2007-02-26 4 S 0 5780 33.12 D 9209080 D Common Stock 2007-02-26 4 S 0 2943 33.13 D 9199137 D Common Stock 2007-02-26 4 S 0 1177 33.14 D 9197960 D Common Stock 2007-02-26 4 S 0 1100 33.15 D 9196860 D Common Stock 2007-02-26 4 S 0 800 33.16 D 9196060 D Common Stock 2007-02-26 4 S 0 100 33.18 D 9195960 D Common Stock 2007-02-26 4 S 0 100 33.19 D 9195860 D Common Stock 2007-02-26 4 S 0 100 33.20 D 9195760 D Common Stock 2007-02-26 4 S 0 300 33.21 D 9195460 D Common Stock 2007-02-26 4 S 0 500 33.22 D 9194960 D Common Stock 2007-02-26 4 S 0 100 33.23 D 9194860 D Common Stock 2007-02-26 4 S 0 200 33.24 D 9194660 D Common Stock 2007-02-26 4 S 0 700 33.26 D 9193960 D Common Stock 2007-02-26 4 S 0 600 33.27 D 9193360 D Common Stock 2007-02-26 4 S 0 300 33.28 D 9193060 D Common Stock 2007-02-26 4 S 0 2300 33.30 D 9190760 D This Form 4 is 2 of 3 Forms 4 being filed to report the sale of stock on February 26, 2007 pursuant to the 10b5-1 trading plan adopted by the Reporting Person. Lisa C. Noecker attorney-in-fact for Fred N. Eshelman 2007-02-27