X0201 42003-12-03 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001033409 ESHELMAN FREDRIC N 6814 TOWLES ROAD WILMINGTON NC 28409 1110Chief Executive OfficerCommon Stock4986263DNot ApplicableStock Options (to buy)30.602003-12-034A0600000A2004-12-032013-12-02Common Stock60000460000D27,188 shares are restricted stock exempt under Section 16(b), Rule 16(b)-3(d)(1).20,000 options will vest on 12/3/04; 20,000 options will vest on 12/3/05 and 20,000 options will vest on 12/3/06.Lisa C. Noecker for Fredric N. Eshelman2003-12-04