The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 5,937 408,329 SH   SOLE   408,329 0 0
ALLENA PHARMACEUTICALS COM 018119107 978 1,651,357 SH   SOLE   1,651,357 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 24,721 1,784,913 SH   SOLE   1,784,913 0 0
ANAPTYSBIO INC COM 032724106 31,265 899,700 SH   SOLE   899,700 0 0
APTINYX INC COM 03836N103 5,028 1,883,244 SH   SOLE   1,883,244 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 174,926 8,434,232 SH   SOLE   8,434,232 0 0
ARVINAS INC COM 04335A105 13,451 163,763 SH   SOLE   163,763 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 19,446 3,746,857 SH   SOLE   3,746,857 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 7,691 951,814 SH   SOLE   951,814 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 33,797 555,240 SH   SOLE   555,240 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 38,686 2,371,918 SH   SOLE   2,371,918 0 0
COGENT BIOSCIENCES INC COM 19240Q201 15,229 1,774,891 SH   SOLE   1,774,891 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 39,328 1,384,293 SH   SOLE   1,384,293 0 0
EPIZYME INC COM 29428V104 1,848 739,369 SH   SOLE   739,369 0 0
ESSA PHARMA INC COM NEW 29668H708 7,717 543,470 SH   SOLE   543,470 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT 12/09/2025 G3710A121 14,890 1,501,000 SH   SOLE   1,501,000 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 9,996 1,654,938 SH   SOLE   1,654,938 0 0
GRITSTONE BIO INC COM 39868T105 60,021 4,667,242 SH   SOLE   4,667,242 0 0
IMAGO BIOSCIENCES INC COM 45250K107 70,449 2,971,274 SH   SOLE   2,971,274 0 0
IMMUNOVANT INC COM 45258J102 4,991 585,759 SH   SOLE   585,759 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 33,362 1,747,622 SH   SOLE   1,747,622 0 0
IVERIC BIO INC COM 46583P102 30,738 1,838,402 SH   SOLE   1,838,402 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 17,266 1,305,087 SH   SOLE   1,305,087 0 0
KRYSTAL BIOTECH INC COM 501147102 53,949 771,250 SH   SOLE   771,250 0 0
MERUS N V COM N5749R100 17,782 559,179 SH   SOLE   559,179 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 56,892 3,566,912 SH   SOLE   3,566,912 0 0
MOLECULAR TEMPLATES INC COM 608550109 5,386 1,374,047 SH   SOLE   1,374,047 0 0
NABRIVA THERAPEUTICS PLC SHS G63637113 255 425,650 SH   SOLE   425,650 0 0
PARDES BIOSCIENCES INC COM 69945Q105 40,229 2,457,507 SH   SOLE   2,457,507 0 0
PASSAGE BIO INC COM 702712100 31,809 5,009,219 SH   SOLE   5,009,219 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 114,625 5,827,415 SH   SOLE   5,827,415 0 0
REGENXBIO INC COM 75901B107 7,711 235,809 SH   SOLE   235,809 0 0
REPLIMUNE GROUP INC COM 76029N106 17,638 650,862 SH   SOLE   650,862 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 3,875 156,000 SH   SOLE   156,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 27,498 1,264,861 SH   SOLE   1,264,861 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101 21,171 886,173 SH   SOLE   886,173 0 0
SUTRO BIOPHARMA INC COM 869367102 26,434 1,776,479 SH   SOLE   1,776,479 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 60,680 2,772,062 SH   SOLE   2,772,062 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 31,886 1,417,157 SH   SOLE   1,417,157 0 0
TRICIDA INC COM 89610F101 17,054 1,783,893 SH   SOLE   1,783,893 0 0
TYRA BIOSCIENCES INC COM 90240B106 17,588 1,250,000 SH   SOLE   1,250,000 0 0
VAXCYTE INC COM 92243G108 54,944 2,309,554 SH   SOLE   2,309,554 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 29,758 1,505,200 SH   SOLE   1,505,200 0 0