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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:    
Net loss $ (22,197,867) $ (14,962,654)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 521,860 392,727
Amortization of deferred financing costs 0 (3,549,328)
Share-based compensation, net 910,884 1,373,968
Fair value of common stock issued for services 0 8,404
Gain on revaluation of derivative warrant liability (81,155) (911,000)
Warrant repricing charged to legal expense 328,000 0
Loss on disposals of assets 278,816 1,114
Impairment charge 9,625,000 0
Financing loss 4,720,000 0
Changes in assets and liabilities:    
Prepaid expenses and other (25,911) (441,603)
Accounts payable 656,556 765,149
Deferred revenue from licensing arrangements 0 (57,321)
Accrued and other 183,953 (442,715)
Net cash used in operating activities (5,079,864) (10,724,603)
Cash Flows from Investing Activities:    
Purchase of property and equipment (55,836) (36,627)
(Increase) decrease in restricted cash (183,938) 250,000
Decrease in security deposit 0 2,076
Proceeds on disposal of property and equipment 126,082 0
Net cash provided by (used in) investing activities (113,692) 215,449
Cash Flows From Financing Activities:    
Proceeds from equity issuances 3,581,500 3,293,397
Proceeds from bridge loans 330,000 0
Principal payments on capital lease obligations 0 (1,362)
Capital contribution 59,325 440,675
Net cash provided by financing activities 3,970,825 3,732,710
Net decrease in cash and cash equivalents (1,222,731) (6,776,444)
Cash and cash equivalents, beginning of year 1,278,941 8,055,385
Cash and cash equivalents, end of year 56,210 1,278,941
Supplemental disclosure of cash flow information:    
Cash paid for interest 15,522 2,154
Cash paid for income taxes 4,110 0
Supplemental disclosure of non-cash financing transactions:    
Deemed dividend on beneficial conversion feature of convertible preferred stock 0 350,000
Director’s fees payable offset against prepaid insurance 272,200  
Accrued legal fees settled with stock 550,000 0
Security deposit offset against accounts payable 9,740 0
Conversion of convertible preferred stock into Common Stock at par value $ 15,000 $ 0