Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Income Statement [Abstract]
Licensing revenues	$ 0	$ 57,321
Operating expenses:
Research and development	2,788,938	4,634,287
Selling, general and administrative	4,325,645	7,350,231
Impairment charge	9,625,000	0
Loss on disposal of property and equipment	278,816	1,114
Depreciation and amortization	521,860	392,727
Total operating expenses	17,540,259	12,378,359
Loss from operations	(17,540,259)	(12,321,038)
Other income (expense):
Financing loss	(4,720,000)	0
Amortization of deferred financing costs	0	(3,549,328)
Interest expense	(15,343)	(1,176)
Other income	0	1,888
Gain on revaluation of derivative warrant liability	81,155	911,000
Other income (expense), net	(4,654,188)	(2,637,616)
Net loss before taxes	(22,194,447)	(14,958,654)
State income taxes	3,420	4,000
Net loss	(22,197,867)	(14,962,654)
Deemed dividend on beneficial conversion feature convertible preferred stock	0	(350,000)
Net loss applicable to common shareholders	$ (22,197,867)	$ (15,312,654)
Net loss per common share, basic and diluted	$ (1.98)	$ (1.24)
Basic and diluted weighted average common shares outstanding	11,231,418	12,308,254