Consolidated Balance Sheets - USD ($)	Dec. 31, 2015	Dec. 31, 2014
Current Assets:
Cash and cash equivalents	$ 56,210	$ 1,278,941
Prepaid and other	244,534	490,824
Total current assets	300,744	1,769,765
Property and equipment, net	267,671	1,138,593
Other assets:
Intangible assets, net	0	9,625,000
Cash restricted pursuant to letters of credit	236,425	52,488
Other assets	250	9,990
Total other assets	236,675	9,687,478
Total assets	805,090	12,595,836
Current liabilities:
Accounts payable	2,176,083	1,801,469
Accrued and other	602,345	968,392
Bridge loans payable	330,000	0
Derivative warrant liability	127,000	208,155
Total current liabilities	3,235,428	2,978,016
Deferred revenue from licensing arrangements, net of current portion	95,535	95,535
Total liabilities	3,330,963	$ 3,073,551
Commitments and contingencies
Stockholders' equity:
Common stock, $0.01 par value, 150,000,000 shares authorized; issued and outstanding 11,124,496 and 12,629,695 shares, respectively	111,243	$ 126,295
Additional paid-in capital	147,412,559	137,292,157
Accumulated deficit	(150,129,933)	(127,932,066)
Total stockholders' equity (deficit)	(2,525,873)	9,522,285
Total liabilities and stockholders' equity (deficit)	805,090	12,595,836
SeriesCPreferredStock [Member]
Stockholders' equity:
Preferred Stock, $0.01 par value; 40,000,000 shares authorized: C - 10,000 shares authorized; issued and outstanding 1,000 shares; D - 3,600,000 shares authorized; issued and outstanding 1,000,000 shares; E - 1,748,613 shares authorized, issued and outstanding; F - 6,000,000 shares authorized; issued and outstanding 5,276,180 and 840,336 shares, respectively	10	10
SeriesDPreferredStock [Member]
Stockholders' equity:
Preferred Stock, $0.01 par value; 40,000,000 shares authorized: C - 10,000 shares authorized; issued and outstanding 1,000 shares; D - 3,600,000 shares authorized; issued and outstanding 1,000,000 shares; E - 1,748,613 shares authorized, issued and outstanding; F - 6,000,000 shares authorized; issued and outstanding 5,276,180 and 840,336 shares, respectively	10,000	10,000
Series E Preferred Stock [Member]
Stockholders' equity:
Preferred Stock, $0.01 par value; 40,000,000 shares authorized: C - 10,000 shares authorized; issued and outstanding 1,000 shares; D - 3,600,000 shares authorized; issued and outstanding 1,000,000 shares; E - 1,748,613 shares authorized, issued and outstanding; F - 6,000,000 shares authorized; issued and outstanding 5,276,180 and 840,336 shares, respectively	17,486	17,486
Series F Preferred Stock [Member]
Stockholders' equity:
Preferred Stock, $0.01 par value; 40,000,000 shares authorized: C - 10,000 shares authorized; issued and outstanding 1,000 shares; D - 3,600,000 shares authorized; issued and outstanding 1,000,000 shares; E - 1,748,613 shares authorized, issued and outstanding; F - 6,000,000 shares authorized; issued and outstanding 5,276,180 and 840,336 shares, respectively	$ 52,762	$ 8,403