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Consolidated Statements of Cash Flows (Unaudited) (USD $)
9 Months Ended 12 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Cash Flows From Operating Activities:          
Net loss $ (15,566,767) $ (10,405,209) $ (12,332,008) $ (10,029,591) $ (4,146,796)
Depreciation and amortization 288,883 75,772 145,155 47,916 109,413
Share-based compensation, net 908,983 920,251 1,409,562 836,866 164,810
Fair value of common stock issued as charitable contribution           113,400
Fair value of common stock and warrants issued for services 89,970 118,465 153,464 448,940 935,144
Fair value of options issued for services          59,471
Gain on revaluation of derivative warrant liability (4,605,986) (201,281) (3,683,676) 1,762,938 (371,345)
Non-cash (gain) loss on extinguishment of debt        1,514 (183,863)
Non-cash interest expense        12,159 35,190
Amortization of discount on note payable 2,879,166 5,556 120,834      
Amortization of non-cash deferred financing costs 726,003 80,667 423,126      
Non-cash loss on disposals of assets    21,272 21,272 5,688   
Non-cash debt financing costs    160,000 455,000      
Cash received from lessor as a lease incentive     236,974      
Accounts receivable    37,065 37,065 104,423 (11,452)
Prepaid expenses and other current assets (51,484) 99,041 98,124 (79,003) 31,436
Other assets (1,500) 9,999 9,999 (576) 1,750
Accounts payable (768,127) 664,190 1,953,921 (240,336) (320,078)
Deferred revenue from licensing arrangements (67,671) (92,781) (5,119) (302,059) (225,868)
Accrued expenses and other liabilities 14,472 637,633 668,642 505,184 178,969
Net cash used in operating activities (16,154,058) (7,869,360) (10,287,665) (6,925,937) (3,629,819)
Cash Flows from Investing Activities:          
Purchase of furniture, equipment and leasehold improvements (237,387) (985,158) (1,487,091) (323,301) (14,415)
Increase in restricted cash (250,000) (157,463) (157,463) 5,510 (265,500)
Net cash used in investing activities (487,387) (1,142,621) (1,644,554) (317,791) (279,915)
Cash Flows From Financing Activities:          
Proceeds from issuance of common stock, net of expenses 21,964,575 6,667 3,278,869 6,439,489 3,886,794
Proceeds from Platinum note payable    1,000,000 3,000,000      
Repayment of Platinum note payable (3,000,000)         
Principal payments for capital lease obligations (1,871) (1,694) (2,288) (2,071) (1,874)
Proceeds from exercise of warrants    212,017 212,018 4,919,346   
Proceeds from exercise of stock options    195,260 195,259 136,790   
Proceeds from issuance of Series D Convertible Preferred Stock and warrants, net of expenses        2,478,701   
Proceeds from bridge notes        1,000,000 250,000
Repayment of bridge notes        (75,000) (50,000)
Net cash provided by financing activities 18,962,704 1,412,250 6,683,858 14,897,255 4,084,920
Net increase (decrease) in cash and cash equivalents 2,321,259 (7,599,731) (5,248,361) 7,653,527 175,186
Cash and cash equivalents, beginning of period 3,747,210 8,995,571 8,995,571 1,342,044 1,166,858
Cash and cash equivalents, end of period 6,068,469 1,395,840 3,747,210 8,995,571 1,342,044
Supplemental Disclosure of Cash Flow Information and Non Cash Financing Transactions:          
Cash paid for interest 114,082 408 515 1,768 2,124
Reclassification of derivative warrant liability to additional paid-in capital   61,520 61,520 2,272,597 200,357
Fair value of common stock issued in connection with settlement agreement   208,000 (82,000) 290,000   
Fair value of Commitment Warrant issued in connection with debt financing   4,840,000 4,840,000      
Fair value of Draw Warrant issued for note payable recorded as discount   1,000,000 3,000,000      
Fair value of Draw Warrant issued for note payable recorded s debt financing costs   160,000 455,000      
Accretion of dividend on Series B Perpetual Redeemable Preferred Stock        157,733 131,659
Deemed dividend on beneficial conversion of Series D Convertible Preferred Stock        1,975,211   
Issuance of common stock in settlement of short term note        35,500 100,000
Issuance of common stock in settlement of accounts payable           23,000
Issuance of common stock in connection with issuance of promissory notes           48,500
Conversion of notes payable and accrued interest into Series D Convertible Preferred Stock        1,006,000   
Conversion of Series D Convertible Preferred Stock into Common Stock        500,000   
Redemption of Series B Perpetual Redeemable Preferred Stock for Series C Preferred Stock in connection with October 27, 2011 warrant exercises        1,701,672   
Fair value of warrants included in stock issuance costs        41,363 468,741
Common stock subscription receivable        6,667 285,000
Cancellation of restricted common stock        5,250   
Deemed dividend on repricing of warrants        $ 4,559,761