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Consolidated Balance Sheets (Unaudited) (USD $)
Sep. 30, 2013
Dec. 31, 2012
Dec. 31, 2011
Current Assets:      
Cash and cash equivalents $ 6,068,469 $ 3,747,210 $ 8,995,571
Cash restricted pursuant to letters of credit 657,463 407,463 250,000
Accounts receivable     37,065
Stock subscriptions receivable     6,667
Deferred financing costs, current portion 968,004 968,004 100,458
Prepaid expenses and other current assets 127,110 75,626 173,750
Total current assets 7,821,046 5,198,303 9,563,511
Property and Equipment, at cost:      
Computer equipment 323,489 367,854 298,290
Office and laboratory equipment (including assets under capitalized leases) 716,531 732,296 624,817
Furniture and fixtures 755,444 728,269 186,837
Manufacturing equipment 111,980 156,435 156,435
Leasehold improvements 825,589 818,939 187,264
Property and equipment, at cost 2,733,033 2,803,793 1,453,643
Less-Accumulated depreciation and amortization (1,146,135) (1,165,398) (1,135,912)
Net property and equipment (including assets under capitalized leases) 1,586,898 1,638,395 317,731
Other Assets:      
Restricted cash     19,739
Intangible assets, net of accumulated amortization 9,625,000 9,625,000 9,625,000
Deferred financing costs, net of current portion 2,823,325 3,549,328   
Other assets 12,066 10,566 826
Total other assets 12,460,391 13,184,894 9,645,565
Total assets 21,868,335 20,021,592 19,526,807
Current Liabilities:      
Accounts payable 1,551,092 2,319,219 365,298
Deferred revenue from licensing arrangements, current portion 90,228 90,228 123,708
Capital lease obligation, current portion 2,017 2,527 2,288
Derivative warrant liability 979,155 5,585,141 1,035,337
Accrued expenses and other current liabilities 1,595,920 1,581,448 965,832
Total current liabilities 4,218,412 9,578,563 2,492,463
Capital lease obligation, net of current portion    1,361 3,888
Note payable, net of discount    120,834   
Deferred revenue from licensing arrangements, net of current portion 22,557 90,228 61,867
Total liabilities 4,240,969 9,790,986 2,558,218
Convertible Preferred Stock:      
Series C, $0.01 par value, authorized 10,000 shares, issued and outstanding 9,974.185 shares at September 30, 2013, December 31, 2012, and December 31, 2011 100 100 100
Series D, $0.01 par value, authorized 3,600,000 shares, issued and outstanding 3,006,000 shares at September 30, 2013 and December 31, 2012 (preference in liquidation of $3,006,000) 30,060 30,060 30,060
Common Stock, $0.01 par value, authorized 150,000,000 shares, issued and outstanding 10,699,990, 4,473,346, and 3,854,400 shares at September 30, 2013, December 31, 2012, and December 31, 2011, respectively 107,003 44,374 38,554
Additional paid-in capital 126,958,986 104,058,087 98,463,225
Common stock subscribed for but not paid for or issued, 33,333 shares at December 31, 2011     6,667
Accumulated deficit (109,468,783) (93,902,015) (81,570,007)
Total stockholders' equity 17,627,366 10,230,606 16,968,589
Total liabilities and stockholders' equity $ 21,868,335 $ 20,021,592 $ 19,526,807