Preferred Stock Statement, Equity Components [Axis] Common Stock Additional Paid-in Capital Common Stock Subscribed Accumulated Deficit Document And Entity Information Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Is Entity a Well-known Seasoned Issuer? Is Entity a Voluntary Filer? Is Entity's Reporting Status Current? Entity Filer Category Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Period Focus Document Fiscal Year Focus Statement of Financial Position [Abstract] ASSETS Current Assets: Cash and cash equivalents Restricted cash Accounts receivable Stock subscriptions receivable Prepaid expenses and other current assets Total current assets Property and Equipment, at cost: Computer equipment Office and laboratory equipment (including assets under capitalized leases) Furniture and fixtures Manufacturing equipment Leasehold improvements Property and equipment, at cost Less-Accumulated depreciation and amortization Net property and equipment (including assets under capitalized leases) Other Assets: Restricted cash Intangible assets, net of accumulated amortization Deposits and other assets Total other assets Total assets LIABILITIES AND STOCKHOLDERS' EQUITY Current Liabilities: Accounts payable Deferred revenue Current portion of notes payable and capital lease obligation, net of discounts Derivative warrant liability Accrued expenses and other liabilities Total current liabilities Notes Payable and capital lease obligation, net of current portion and discounts Deferred revenue, net of current portion Total liabilities Commitments Stockholders' Equity: Perpetual Redeemable Preferred Stock: Series B, $0.01 par value, authorized 40,000 shares, issued and outstanding 154.3940 shares at December 31, 2010 Convertible Preferred Stock: Series C, $0.01 par value, authorized 10,000 shares, issued and outstanding 9,974.185 and 4,918.100 shares at December 31, 2011 and 2010, respectively Series D, $0.01 par value, authorized 3,600,000 shares, issued and outstanding 3,006,000 shares at December 30, 2011 (preference in liquidation of $3,006,000 at December 31, 2011) Common stock, $0.01 par value, authorized 100,000,000 shares, issued and outstanding 38,543,944 and 31,126,245 shares at December 31, 2011 and 2010, respectively Additional paid-in capital Common stock subscribed for but not paid for or issued, 33,333 and 285,000 shares at December 31, 2011 and 2010, respectively Accumulated deficit Total stockholders' equity Total liabilities and stockholders' equity Series B, par value Series B, authorized Series B, outstanding Series B, Share Issued Convertible Preferred Stock: Series C, par value Series C, authorized Series C, outstanding Series C, Share Issued Series D, par value Series D, authorized Series D, outstanding Series D, Share Issued Common stock, par value Common stock, authorized Common stock, outstanding Common stock, Share Issued Income Statement [Abstract] Licensing revenue Other revenue Total revenues Operating Expenses: Research and development Selling, general and administrative Total operating expenses Loss from operations Other Income (Expense): Interest income Interest expense Qualified therapeutic research grant Gain (loss) on extinguishment of debt/payables Gain (loss) on disposal of assets Derivative warrant liability gain (loss) Other income (expense), net Net loss Deemed dividend on beneficial conversion feature of Series D Convertible Preferred Stock Deemed dividend on warrant repricings Accretion of dividends on Convertible Perpetual Redeemable Preferred Stock Net loss applicable to common shareholders Net loss per common share, basic and diluted Basic and diluted weighted average common shares outstanding Statement [Table] Statement [Line Items] Beginning balance, Shares Beginning balance, Amount Exercise of warrants, Shares Exercise of warrants, Amount Series B Preferred Stock redeemed for Series C Preferred Stock in warrant exercise, Shares Series B Preferred Stock redeemed for Series C Preferred Stock in warrant exercise, Amount Share-based payments - restricted stock, net of forfeitures, Shares Share-based payments - restricted stock, net of forfeitures, Amount Share-based payments - options, net of forfeitures Fair value of warrants issued for services Fair value of options issued for services Common Stock issued to charitable organization, Shares Common Stock issued to charitable organization , Amount Issuance of Common Stock, net of cash issuance costs of $188,333 and non-cash costs of $468,741, Shares Issuance of Common Stock, net of cash issuance costs of $188,333 and non-cash costs of $468,741, Amount Fair value of fully vested Common Stock issued for services, Shares Fair value of fully vested Common Stock issued for services, Amount Fair value of derivative warrant liabilities reclassified to additional paid-in capital Dividends on Series B Preferred Stock, Shares Dividends on Series B Preferred Stock, Amount Common Stock subscription, 285,000 shares Issuance of Common Stock and warrants, net of cash issuance costs of $109,636 and non-cash costs of $41,363, Shares Issuance of Common Stock and warrants, net of cash issuance costs of $109,636 and non-cash costs of $41,363, Amount Issuance of Series D Preferred Stock and warrants, net of cash issuance costs of $21,299, Shares Issuance of Series D Preferred Stock and warrants, net of cash issuance costs of $21,299, Amount Series B Preferred Stock dividend paid-in-kind, Shares Series B Preferred Stock dividend paid-in-kind, Amount Common Stock issued in Series D Preferred Stock conversion, Shares Common Stock issued in Series D Preferred Stock conversion, Amount Common Stock and warrants issued to settle short-term note, Shares Common Stock and warrants issued to settle short-term note, Amount Exercise of stock options, Shares Exercise of stock options, Amount Net Loss Ending balance, Shares Ending balance, Amount Statement of Cash Flows [Abstract] Cash Flows From Operating Activities: Net loss Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization Share-based compensation Fair value of common stock issued for charitable contribution Fair value of common stock and warrants issued for services Fair value of options issued for services Derivative warrant liability (gain) loss Non-cash (gain) loss on extinguishment of debt Non-cash interest expense Non-cash loss on disposal of assets Changes in assets and liabilities: Accounts receivable Prepaid expenses and other current assets Deposits and other assets Accounts payable Deferred revenue Accrued expenses and other liabilities Net cash used in operating activities Cash Flows from Investing Activities: Purchase of property and equipment Decrease (increase) in restricted cash Net cash used in investing activities Cash Flows From Financing Activities: Proceeds from the exercise of warrants Proceeds from issuance of common stock and warrants, net of issuance costs Principal payments for capital lease obligations Proceeds from issuance of Series D Convertible Preferred Stock and warrants, net of issuance costs Proceeds from bridge notes Repayment of bridge notes Proceeds from exercise of stock options, net of forfeitures Net cash provided by financing activities Net increase in cash and cash equivalents Cash and cash equivalents, beginning of period Cash and cash equivalents, end of period Supplemental Disclosure of Cash Flow Information and Non Cash Financing Transactions: Cash paid for interest Accretion of dividend on Series B Perpetual Redeemable Preferred Stock Issuance of common stock in settlement of short term note Issuance of common stock in settlement of accounts payable Issuance of common stock in connection with issuance of promissory notes Conversion of notes payable and accrued interest into Series D Convertible Preferred Stock Conversion of Series D Convertible Preferred Stock into Common Stock Deemed dividend on beneficial conversion of Series D Convertible Preferred Stock Redemption of Series B Perpetual Redeemable Preferred Stock for Series C Preferred Stock in connection with October 27, 2011 warrant exercises Reclassification of derivative warrant liability to additional paid-in capital Fair value of warrants included in stock issuance costs Common stock subscription receivable Cancellation of restricted Common Stock Deemed dividend on repricing of warrants Fair value of restricted stock issued in connection with settlement agreement Notes to Financial Statements Note 1. ORGANIZATION AND BASIS OF PRESENTATION Note 2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Note 3. INTANGIBLE ASSETS Note 4. OPERATING LEASE COMMITMENTS Note 5. NOTES PAYABLE AND CAPITAL LEASE OBLIGATION Note 6. DERIVATIVE WARRANT LIABILITY Note 7. PREFERRED STOCK Note 8. COMMON STOCK Note 9. STOCK OPTIONS Note 10. WARRANTS Note 11. INCOME TAXES Note 12. LICENSING AND OTHER REVENUE AND RELATED ACCOUNTS RECEIVABLE Note 13. Litigation Note 14. SUBSEQUENT EVENTS Common Stock, Share Subscribed but Unissued, Subscriptions Receivable Assets, Current OfficeAndLaboratoryEquipment Property, Plant and Equipment, Gross Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Property, Plant and Equipment, Net Restricted Cash and Cash Equivalents, Noncurrent Assets, Noncurrent Assets Liabilities, Current Liabilities Liabilities and Equity ConvertiblePreferredStockAbstract Revenue, Net Operating Expenses Operating Income (Loss) Interest Expense Nonoperating Income (Expense) Net Income (Loss) Available to Common Stockholders, Basic Shares, Issued FairValueOptionIssuedForServices Increase (Decrease) in Accounts Receivable Increase (Decrease) in Prepaid Expense and Other Assets Increase (Decrease) in Other Noncurrent Assets Increase (Decrease) in Accounts Payable Increase (Decrease) in Deferred Revenue Increase (Decrease) in Accrued Liabilities Net Cash Provided by (Used in) Operating Activities Payments to Acquire Machinery and Equipment Increase (Decrease) in Restricted Cash Net Cash Provided by (Used in) Investing Activities Repayments of Long-term Capital Lease Obligations Repayments of Short-term Debt Net Cash Provided by (Used in) Financing Activities ComputerEquipment Period end amount of property, plant and equipment (PPE) related to regulated assets common to business units. DeemedDividendOnBeneficialConversionFeatureOfSeriesDConvertiblePreferredStock DeemedDividendOnRepricingOfWarrants BasicAndDilutedWeightedAverageCommonSharesOutstanding FairValueOfCommonStockIssuedForCharitableContributions FairValueOfCommonStockAndWarrantsIssuedForServices NoncashGainLossOnDisposalOfAssets NoncashGainLossOnExtinguishmentOfDebt DerivativeWarrantLiabilityTextBlock WarrantsTextBlock PerpetualRedeemablePreferredStockAbstract ConvertiblePreferredStockAbstract SeriesB0.01ParValueAuthorized40000SharesIssuedAndOutstanding154.3940SharesAtDecember312011And2010Respectively CommonStockSubscribedMember ExerciseOfStockOptionsAmount ExerciseOfStockOptionsShares CommonStockAndWarrantsIssuedToSettleShorttermNoteAmount CommonStockAndWarrantsIssuedToSettleShorttermNoteShares CommonStockIssuedInSeriesDPreferredStockConversionAmount CommonStockIssuedInSeriesDPreferredStockConversionShares SeriesBPreferredStockDividendPaidinkindAmount SeriesBPreferredStockDividendPaidinkindShares IssuanceOfSeriesDPreferredStockAndWarrantsNetOfCashIssuanceCostsOf21299Amount IssuanceOfSeriesDPreferredStockAndWarrantsNetOfCashIssuanceCostsOf21299Shares IssuanceOfCommonStockAndWarrantsNetOfCashIssuanceCostsOf109636AndNoncashCostsOf41363Amount IssuanceOfCommonStockAndWarrantsNetOfCashIssuanceCostsOf109636AndNoncashCostsOf41363Shares CommonStockSubscription DividendsOnSeriesBPreferredStockAmount DividendsOnSeriesBPreferredStockShares FairValueOfDerivativeWarrantLiabilitiesReclassifiedToAdditionalPaidinCapital FairValueOfFullyVestedCommonStockIssuedForServicesAmount FairValueOfFullyVestedCommonStockIssuedForServicesShares IssuanceOfCommonStockNetOfCashIssuanceCostsOf188333AndNoncashCostsOf468741Amount IssuanceOfCommonStockNetOfCashIssuanceCostsOf188333AndNoncashCostsOf468741Shares CommonStockIssuedToCharitableOrganizationAmount CommonStockIssuedToCharitableOrganizationShares SeriesBAuthorized SeriesBOutstanding SeriesCAuthorized SeriesCOutstanding SeriesDAuthorized SeriesDOutstanding SeriesBParValue SeriesDParValue SeriesDShareIssued SeriesCShareIssued SeriesCParValue SeriesBShareIssued Stock Isused During Period Value Stock Warrants Exercised Exercise of Warrants During Period, Shares Issuance of Common Stock in Settlement of Short Term Note Issuance of Common Stock in Settlement of Accounts Payable Issuance of Common Stock in Connection with Issuance of Promissory Notes Deemed Dividend on Beneficial Conversion Feature of Series D Convertible Preferred Stock Conversion of Notes Payable and Accrued Interest into Series D Convetible Preferred Stock Conversion of Series D Convertible Prefered Stock into Common Stock Reclassification of Derivative Liability to Additional Paid In Capital Fair Value of Warrants included in Stock Issuance Costs Deemed Dividend Warrants Repricing Fair Value of Restricted Stock issued in connection with Settlement Agreement Common Stock Subscriptions Receivable Redemption of Series B Perpetual Redeemable Preferred Stock for Series C Preferred Stock in connection with October 27, 2011 Warrant Exercises SeriesC0.01ParValueAuthorized10000SharesIssuedAndOutstanding9974.185SharesAnd4918.100SharesAtDecember312011And2010 Fair Value Option Issued for Services SeriesBPreferredStockRedeemedForSeriesCPreferredStockInWarrantExerciseShares SeriesBPreferredStockRedeemedForSeriesCPreferredStockInWarrantExerciseValue FairValueWarrantsIssuedForServices FairValueOptionsIssuedForServices