X0306 4 2022-08-08 0 0001029142 DYNAVAX TECHNOLOGIES CORP DVAX 0001286710 CANO FRANCIS C/O DYNAVAX TECHNOLOGIES CORPORATION 2100 POWELL STREET, SUITE 720 EMERYVILLE CA 94608 1 0 0 0 Common Stock 2022-08-08 4 M 0 15000 4.97 A 35834 D Common Stock 2022-08-08 4 S 0 15000 17.17 D 20834 D Stock Option (Right to Buy) 4.97 2022-08-08 4 M 0 15000 D 2026-05-29 Common Stock 15000 0 D This transaction was executed in multiple trades at prices ranging from $17.16 to $17.20; the price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which the transactions were effected upon request to the SEC staff, Dynavax, or a security holder of Dynavax. These options fully-vested on May 30, 2020, upon the one-year anniversary of the grant date. Not applicable. Francis R. Cano, Ph.D., by /s/ Trevor Dutcher, Attorney-in-Fact 2022-08-10