CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited) (USD $) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Income Statement [Abstract]
Net revenues	$ 17,381,984	$ 20,573,401	$ 36,433,536	$ 42,651,274
Costs and operating expenses:
Cost of product sales	8,704,669	11,162,350	18,660,619	24,239,797
Selling, general and administrative expense	13,743,559	13,141,447	27,367,009	27,220,635
Research and development expense	345,579	1,792,184	1,314,433	2,999,300
Depreciation and amortization expense	1,969,159	2,276,992	4,159,626	4,101,700
Loss on disposal of equipment	152,720	4,880	152,720	4,880
Loss on sale of PML (including impairment charge)	215,401		6,672,367
Total costs and operating expenses	25,131,087	28,377,853	58,326,774	58,566,312
Loss from operations	(7,749,103)	(7,804,452)	(21,893,238)	(15,915,038)
Other income (expense):
Change in fair value of put right		(1,830,062)		(3,970,789)
Change in fair value of contingent consideration				283,000
Interest expense, net	(2,233,082)	(1,632,569)	(3,497,334)	(2,709,184)
Gain on sale of investment		3,605,263		3,605,263
Total loss income, net	(2,233,082)	142,632	(3,497,334)	(2,791,710)
Loss before income taxes	(9,982,185)	(7,661,820)	(25,390,572)	(18,706,748)
Income tax benefit	3,749,000	1,985,000	9,615,000	5,119,000
Net loss	(6,233,185)	(5,676,820)	(15,775,572)	(13,587,748)
Other comprehensive (loss) income
Unrealized gains during period, net of tax of $437,900 and ($411,000) for the three and six months ended June 30, 2013, respectively		746,645		(702,000)
Reclassification adjustment for net realized gain included in net loss, net of tax of ($1,322,000) for both the three and six months ended June 30, 2013		(2,273,118)		(2,273,118)
Comprehensive loss	$ (6,233,185)	$ (7,203,293)	$ (15,775,572)	$ (16,562,866)
Net Loss per share, basic	$ (0.16)	$ (0.15)	$ (0.42)	$ (0.38)
Net Loss per share, diluted	$ (0.16)	$ (0.15)	$ (0.42)	$ (0.38)
Weighted-average common shares, basic	37,828,218	37,114,717	37,551,144	35,738,469
Weighted-average common shares, diluted	37,828,218	37,114,717	37,551,144	35,738,469