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9. Stockholders’ Equity (Details) - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Weighted average of the assumptions used to value stock options on the date of grant    
Weighted average expected stock price volatility 86.40% 85.00%
Estimated dividend yield 0.00% 0.00%
Risk-free interest rate 2.70% 2.10%
Expected life of option (in years) 6 years 108 days 6 years 72 days
Weighted average grant date fair value per option $ 1.83 $ 1.86