X0306 4 2017-08-08 0 0001024126 PERNIX THERAPEUTICS HOLDINGS, INC. PTX 0001639479 Golembiewski Michael Joseph C/O PERNIX THERAPEUTICS HOLDINGS, INC. 10 NORTH PARK PLACE, SUITE 201 MORRISTOWN NJ 07960 0 1 0 0 VP Finance, Controller, CAO Common Stock 2017-08-08 4 A 0 3300 0 A 3300 D Stock Option (right to buy) 2.92 2017-08-08 4 A 0 10000 0 A 2027-08-08 Common Stock 10000 10000 D Represents a grant of restricted share units that vest in four equal annual installments of 825 shares over a four-year period, with the first installment vesting on August 8, 2018, which is the one-year anniversary of the grant date. The stock option vests in four equal annual installments of 2,500 shares over a four-year period, with the first installment vesting at the close of business on August 8, 2018, which is the one-year anniversary of the grant date. /s/ Michael J. Golembiewski 2017-08-09