X0306 4 2017-07-27 0 0001024126 PERNIX THERAPEUTICS HOLDINGS, INC. PTX 0001337409 Sedor John A 10 N. PARK PLACE MORRISTOWN NJ 07960 1 1 0 0 Board Chairman and CEO Common Stock 2017-07-27 4 F 0 13293 3.15 D 117807 D No shares were sold - these shares were withheld by the Issuer to satisfy tax withholding requirements in connection with the insider's exercise of his withholding right following the vesting of restricted share units. Consists of (x) 30,407 shares of common stock and (y) the unvested amount of previously-awarded restricted share units that vest in two equal installments of 43,700 shares, with the next installment vesting on July 26, 2018 and the final installment vesting on July 26, 2019. /s/ John A. Sedor 2017-07-31