8. Stockholders’ Equity (Details 1) $ / shares in Units, shares in Thousands, $ in Thousands	6 Months Ended
	Jun. 30, 2017 USD ($) $ / shares shares
Option Shares
Outstanding at December 31, 2016 | shares	650
Granted | shares	38
Exercised | shares	0
Cancelled | shares	(38)
Expired | shares	0
Outstanding at June 30, 2017 | shares	650
Vested and expected to vest, as of June 30, 2017 | shares	517
Vested and exercisable, as of June 30, 2017 | shares	133
Option Average Exercise Price
Outstanding at December 31, 2016 | $ / shares	$ 25.85
Granted | $ / shares	2.89
Exercised | $ / shares	0
Cancelled | $ / shares	46.60
Expired | $ / shares	0
Outstanding at June 30, 2017 | $ / shares	23.49
Vested and expected to vest, as of June 30, 2017 | $ / shares	27.38
Vested and exercisable, as of June 30, 2017 | $ / shares	$ 56.17
Option Weighted Average Remaining Contractual Life Years
Options outstanding at June 30, 2017	8 years 252 days
Options vested and expected to vest, as of June 30, 2017	8 years 180 days
Options vested and exercisable, as of June 30, 2017	7 years 72 days
Option Aggregate Intrinsic Value
Exercised | $	$ 0
Options outstanding at June 30, 2017 | $	291
Options vested and expected to vest as of June 30, 2017 | $	197
Options vested and exercisable as of June 30, 2017 | $	$ 0