X0202 4 2006-10-11 0 0001162192 AVALON PHARMACEUTICALS INC AVRX 0001024008 KABAKOFF DAVID S 20358 SENECA MEADOWS PARKWAY GERMANTOWN MD 20876 1 0 0 0 Stock Option (Right to Buy) 2.78 2006-10-11 4 A 0 10000 2.78 A Common Stock 10000 10000 D The option vests in equal monthly installments over the course of two years from the grant date. The option will expire at the close of business at the Issuer's headquarters on the day before the 10th anniversary of the grant of the option. The option will expire earlier if the reporting person's service to the Issuer terminates. If the reporting person's service to the Issuer terminates for any reason, other than death, disability or cause, then the option will expire at the close of business at the Issuer's headquarters on the 90th day after the reporting person's termination date. /s/ Thomas G. David, Esq. Attorney-in-fact 2006-10-13