X0303 4 2009-09-10 0 0001333248 CADENCE PHARMACEUTICALS INC CADX 0001024007 GARNER CAM L C/O CADENCE PHARMACEUTICALS, INC. 12481 HIGH BLUFF DRIVE, SUITE 200 SAN DIEGO CA 92130 1 0 0 0 Common Stock 2009-09-10 4 S 0 35000 11.00 D 540888 I By Garner Family Trust Common Stock 486595 I By Garner Investments LLC 41,640 of these shares are subject to the Company's right to repurchase as of the date of this report. 7,094 shares vest and are no longer subject to the Company's right to repurchase on the 1st of each month until 12/01/2009 and approximately 4,072 vest and are no longer subject to the Company's right to repurchase on the 1st of each month until 02/01/2010. Mr. Garner is the trustee of this trust. Mr. Garner is the managing member of Garner Investments, LLC. Hazel M. Aker Attorney-in-fact 2009-09-11