X0303 4 2009-06-24 0 0001333248 CADENCE PHARMACEUTICALS INC CADX 0001024007 GARNER CAM L C/O CADENCE PHARMACEUTICALS, INC. 12481 HIGH BLUFF DRIVE, SUITE 200 SAN DIEGO CA 92130 1 0 0 0 Stock Option (right to buy) 9.37 2009-06-24 4 A 0 12500 A 2019-06-23 Common Stock 12500 12500 D Shares shall vest in twelve equal monthly installments of 1/12 of the original number of shares subject to such option beginning upon the Vesting Commencement Date of July 1, 2009, subject to such individual's continuing service on the Board through each such date. Not applicable to this transaction. /s/ Hazel M. Aker Attorney-in-fact 2009-06-26