X0201 3 2004-03-31 0 0001172480 SANTARUS INC SNTS 0001024004 HALE DAVID F 2110 RUTHERFORD ROAD CARLSBAD CA 92008 1 0 0 0 Common Stock 55711.0000 I By Family Trust. Series C Preferred Stock 6.0386 Common Stock 67053.0000 I By Family Trust Series D Preferred Stock 4.3950 Common Stock 28571.0000 I By Family Trust Series C Preferred Stock Warrant (right to buy) 6.0386 2000-12-21 2006-05-01 Common Stock 6623.0000 I By Family Trust Series C Preferred Stock Warrant (right to buy) 6.0386 2001-01-17 2006-05-01 Common Stock 6623.0000 I By Family Trust Stock Option (right to buy) 0.8750 2003-05-22 2013-05-22 Common Stock 11428.0000 D Stock Option (right to buy) 1.2250 2003-07-30 2013-07-30 Common Stock 4285.0000 D Stock Option (right to buy) 9.4500 2004-02-26 2014-02-26 Common Stock 10000.0000 D By Hale Family Trust dated February 10, 1986. These securities will automatically convert to common stock upon the consummation of Santarus' initial public offering. Immediately convertible. The expiration date is not relevant to this transaction. Currently exercisable as to 16,460 shares of Series C Preferred Stock at an exercise price of $2.43. Upon the consummation of Santarus' initial public offering, the warrant will be exercisable as to 6,623 shares of common stock at an exercise price of $6.0386. Fully vested. Vested 100% on 2/26/05. /s/ Debra P. Crawford Attorney-in-fact 2004-03-31