X0202 3 2004-06-15 0 0001053221 METABASIS THERAPEUTICS INC MBRX 0001024004 HALE DAVID F 2110 RUTHERFORD ROAD CARLSBAD CA 92008 1 0 0 0 Common Stock 33085 I By Family Trust Stock Option (Right to Buy) 1.46 2013-03-27 Common Stock 1316 D Stock Option (Right to Buy) 1.46 2014-03-10 Common Stock 1316 D Series D Convertible Preferred Stock Common Stock 14140 I By Family Trust Warrant to Purchase Series D Convertible Preferred Stock 1.50 Series D Convertible Preferred Stock 3111 I By Family Trust By Hale Family Trust dated February 10, 1986. Beginning on March 28, 2003, the shares subject to the option vest in 12 monthly installments. Beginning on March 8, 2004, the shares subject to the option vest in 12 monthly installments. Immed. Not applicable. Each share of Series D Preferred Stock is convertible into 0.17 of a share of Common Stock at the option of the holder and will automatically convert upon the completion of the issuer's initial public offering. David F. Hale 2004-06-15