Segment Information (Tables)

6 Months Ended

Jun. 30, 2014

Segment Information

Segment revenues, operating income and total assets

	Early Development			Late-Stage Development			Other Reconciling Items			Total
Three months ended June 30, 2014
Total revenues from external customers	$	231,198		$	408,258		$	47,652	(a)	$	687,108
Operating income	$	(22,424	)(d)	$	87,051	(e)	$	(45,363	)(b)	$	19,264
Total assets	$	1,083,416		$	1,230,042		$	225,186	(c)	$	2,538,644
Three months ended June 30, 2013
Total revenues from external customers	$	214,582		$	377,716		$	51,678	(a)	$	643,976
Operating income	$	21,882	(d)	$	79,500	(e)	$	(49,872	)(b)	$	51,510
Total assets	$	1,123,348		$	1,001,028		$	216,898	(c)	$	2,341,274
Six months ended June 30, 2014
Total revenues from external customers	$	449,422		$	810,086		$	93,888	(a)	$	1,353,396
Operating income	$	(2,948	)(d)	$	180,103	(e)	$	(91,003	)(b)	$	86,152
Total assets	$	1,083,416		$	1,230,042		$	225,186	(c)	$	2,538,644
Six months ended June 30, 2013
Total revenues from external customers	$	421,858		$	750,639		$	105,814	(a)	$	1,278,311
Operating income	$	38,439	(d)	$	162,449	(e)	$	(101,127	)(b)	$	99,761
Total assets	$	1,123,348		$	1,001,028		$	216,898	(c)	$	2,341,274

(a) Represents revenues associated with reimbursable out-of-pocket expenses.

(b) Represents corporate expenses (primarily information technology, marketing, communications, human resources, finance, legal and stock-based compensation expense). Corporate expenses include charges associated with restructuring and cost reduction actions of $397 and $2,658 for the three and six months ended June 30, 2014, respectively, and $2,308 and $3,027 for the three and six months ended June 30, 2013, respectively.

(c) Represents corporate assets.

(d) Early Development operating income includes asset impairment charges totaling $52,564 for both the three and six months ended June 30, 2014, and charges associated with restructuring and cost reduction actions of $651 and $2,281 for the three and six months ended June 30, 2014, respectively, and $2,342 and $5,895 for the three and six months ended June 30, 2013, respectively.

(e) Late-Stage Development operating income includes charges associated with restructuring and cost reduction actions of $3,150 and $3,396 for the three and six months ended June 30, 2014, respectively, and $1,363 and $3,261 for the three and six months ended June 30, 2013, respectively.