Segment Information (Tables)

6 Months Ended

Jun. 30, 2013

Segment Information

Segment revenues, operating income and total assets

	Early Development			Late-Stage Development			Other Reconciling Items			Total
Three months ended June 30, 2013
Total revenues from external customers	$	214,582		$	377,716		$	51,678	(a)	$	643,976
Operating income	$	21,882	(d)	$	79,500	(e)	$	(49,872	)(b)	$	51,510
Total assets	$	1,123,348		$	1,001,028		$	216,898	(c)	$	2,341,274
Three months ended June 30, 2012
Total revenues from external customers	$	219,683		$	323,099		$	42,263	(a)	$	585,045
Operating (loss) income	$	(33,092	)(d)	$	68,027	(e)	$	(38,864	)(b)	$	(3,929	)
Total assets	$	1,098,047		$	814,086		$	225,203	(c)	$	2,137,336
Six months ended June 30, 2013
Total revenues from external customers	$	421,858		$	750,639		$	105,814	(a)	$	1,278,311
Operating income	$	38,439	(d)	$	162,449	(e)	$	(101,127	)(b)	$	99,761
Total assets	$	1,123,348		$	1,001,028		$	216,898	(c)	$	2,341,274
Six months ended June 30, 2012
Total revenues from external customers	$	431,351		$	642,272		$	85,330	(a)	$	1,158,953
Operating (loss) income	$	(21,784	)(d)	$	140,466	(e)	$	(76,489	)(b)	$	42,193
Total assets	$	1,098,047		$	814,086		$	225,203	(c)	$	2,137,336

(a) Represents revenues associated with reimbursable out-of-pocket expenses.

(b) Represents corporate expenses (primarily information technology, marketing, communications, human resources, finance, legal and stock-based compensation expense). Corporate expenses include charges associated with restructuring and cost reduction actions of $2,308 and $3,027 for the three and six months ended June 30, 2013, respectively, and restructuring costs of $291 for the three and six months ended June 30, 2012.

(c) Represents corporate assets.

(d) Early Development operating income includes restructuring and cost reduction actions of $2,342 and $5,895 for the three and six months ended June 30, 2013, respectively, and restructuring costs of $9,197, an inventory impairment charge of $20,781 and a goodwill impairment charge of $17,959 for the three and six months ended June 30, 2012.

(e) Late-Stage Development operating income includes restructuring costs of $1,363 and $3,261 for the three and six months ended June 30, 2013, respectively, and restructuring costs of $179 for the three and six months ended June 30, 2012.