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Statements of Stockholders' Equity (USD $)
Total
Accumulated Deficit
Class C Special Shares
Common Stock
Balance at Dec. 31, 2008 $ 13,826,419 $ (71,906,660) $ 391 $ 85,732,688
Balance (in shares) at Dec. 31, 2008     391,286 27,042,764
Issuance of common shares        
Stock option expense 1,254,503     1,254,503
Stock warrant expense 64,103     64,103
Registered direct offerings of common shares and warrants, net 11,352,751     11,352,751
Registered direct offerings of common shares and warrants, net (in shares)       6,000,000
Issuance of common shares pursuant to Cell Genesys, Inc. transaction 36,800,043     36,800,043
Issuance of common shares pursuant to Cell Genesys, Inc. transaction (in shares)       20,219,804
Credit equity financing facility 60,343     60,343
Net loss (47,527,768) (47,527,768)    
Balance at Dec. 31, 2009 15,830,394 (119,434,428) 391 135,264,431
Balance (in shares) at Dec. 31, 2009     391,286 53,262,568
Issuance of common shares        
Stock option exercise 2,014     2,014
Stock option exercise (in shares)       1,334
Stock option expense 992,757     992,757
Stock warrant expense 65,529     65,529
Registered direct offerings of common shares and warrants, net 48,452,644     48,452,644
Registered direct offerings of common shares and warrants, net (in shares)       28,127,228
Net loss (46,196,216) (46,196,216)    
Balance at Dec. 31, 2010 19,147,122 (165,630,644) 391 184,777,375
Balance (in shares) at Dec. 31, 2010     391,286 81,391,130
Issuance of common shares        
Stock option exercise 32,442     32,442
Stock option exercise (in shares)       19,167
Warrant exercises - various 24,062     24,062
Warrant exercises - various (in shares)       8,750
Stock option expense 1,177,683     1,177,683
Stock warrant expense 204,980     204,980
Underwritten offering of common shares, net 44,961,137     44,961,137
Underwritten offering of common shares, net (in shares)       16,000,000
Registered direct offerings of common shares and warrants, net 23,876,370     23,876,370
Registered direct offerings of common shares and warrants, net (in shares)       12,199,482
Net loss (51,608,504) (51,608,504)    
Balance at Dec. 31, 2011 $ 37,815,292 $ (217,239,148) $ 391 $ 255,054,049
Balance (in shares) at Dec. 31, 2011     391,286 109,618,529